Sr. Principal Systems Engineer - Medical Device

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About the role

We anticipate the application window for this opening will close on - 12 Oct 2026   Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life Cardiac Ablation Solutions develops technologies and therapies used to diagnose and treat cardiac arrhythmias. This team partners across systems engineering, product development, field engineering, technical services, marketing, and clinical stakeholders to ensure successful integration of electrophysiology systems within hospital environments and to support product performance throughout the product lifecycle. This position may be based in Mounds View, Minnesota or Newton, Massachusetts and follows an onsite work model with a minimum of four days per week in the office.                     As a Sr. Principal Systems Engineer, you will provide technical leadership for system integration and refine your systems engineering skills to conduct interface testing, both within the system and during commercial support, as well as integrating the system into Electrophysiology cath lab hospital environments. Primary Responsibilities  • Participate on cross-functional development teams in the creation of integration, characterization, and troubleshooting testing, training, and guidance documents.  • Develop expertise in the application of systems engineering principles and identify opportunities for applying systems engineering within work assigned to the team.  • Support marketing, field engineering, technical services, and training and education in technical questions.   • Propose and implement changes to improve systems and/or processes.  • Travel Required Qualifications  • Bachelor's degree and a minimum of 10 years of relevant experience  • OR Master’s with a minimum of 8 years of relevant experience  • OR PhD with 6 years of relevant experience  • Advanced Systems Engineering experience defining systems architecture • Medical device experience   Preferred Qualifications  • Advanced understanding of Electrophysiology and comfort in the hospital environment  • Experience with the application of Design Controls for medical devices  • Demonstrated ability to create strategies and influence cross-functionally        #LI-MDT      For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required. Physical Job Requirements The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.  The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role. U.S. Work Authorization & Sponsorship At Medtronic, we

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