Jobs / United States / Astrazeneca Pharmaceuticals Lp
Associate Principal Scientist - Formulation and Process Design
Astrazeneca Pharmaceuticals Lp · 🇺🇸 US - Durham - NC
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Astrazeneca Pharmaceuticals Lp paid sponsored hires in similar roles15 certified filings for “Associate Director Oncology Outcomes Research” (Medical Scientists, Except Epidemiologists) in MD: $126k–$185k, median $140k. Most were filed at wage level II (47%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
The US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Astrazeneca Pharmaceuticals Lp →
About the role
About AstraZeneca: AstraZeneca is a global, science-led biopharmaceutical company and our innovative medicines are used by millions of patients worldwide. This is the place to make an impact. Here we ensure everyone can reach their full potential, perform at their best and make a valued contribution to the enterprise! About Pharmaceutical Technology & Development (PT&D) and Global Product Development (GPD): PT&D is the bridge that turns brilliant science into real medicines, spanning the entire value chain—from early toxicology and clinical supplies to technology that enables robust commercial manufacture. Within PT&D, GPD leads the late‑stage design and development of drug products across a range of dosage forms. We develop the formulation, manufacturing process, and scientific understanding needed to scale, launch, and sustain new medicines. You’ll collaborate in highly multidisciplinary teams with engineers and pharmaceutical scientists to advance life-changing medicines for patients. The Opportunity: We are seeking an Associate Principal Scientist within Formulation and Process Design, that can balance formulation development and process engineering with a passion for application of digital tools with experience in solid dosage product development (tablets, capsules). In this role you will work closely with a team of colleagues in a multi-disciplinary environment to assess, design, develop and deliver high quality clinical and commercial formulations and processes. You can expect to contribute to programs at laboratory scale with line of sight for commercial manufacture by using modelling and simulation approaches as first intent combined with hands-on experimental work as needed. You will play a key role in leading the formulation aspects of projects in late-stage development spanning an exciting portfolio of oral solid dosage forms (including Continuous Direct Compression). You will be an important member of a multidisciplinary team, providing input to the overall product development, designing and executing lab based and pilot plant work packages and driving the development and implementation of in silico tools to support and accelerate development. You will be a recognized problem solver and team player who thrives under pressure and has a passion for ensuring product robustness through the development of manufacturing processes which are well understood, controlled, and capable of meeting long‑term commercial and patient needs. Key Responsibilities: • Lead formulation input for the design and development of robust oral solid dosage forms. • Lab-based formulation and process development: plan and execute lab-scale experiments to facilitate project decisions. • Shape the scientific and technical direction of product development activities through formulation understanding and process design and control. • Help define and optimize critical process parameters (CPPs) and integrate them into control strategies. • Lead or contribute to technology transfer, risk assessment, process validation and scale‑up. • Apply modelling, simulation, digital twins and predictive tools to enhance process understanding. • Solve key technical challenges with direct impact on current project delivery. • Drive a culture of creativity, innovation and scientific excellence. • Cross-functional collaboration: Contribute to integrated drug product development plans within a multidisciplinary team. • Work hands-on to generate data as well as work collaboratively with other experimentalists with different backgrounds to identify/use/drive digital applications as first intent to strategically direct experimentation. • Be part of cross-functional project teams focusing on developing drug products ranging from both early to late-stage developmen