Jobs / United States / Astrazeneca Pharmaceuticals Lp
Senior Medical Director - Biologics
Astrazeneca Pharmaceuticals Lp · 🇺🇸 US - Wilmington - DE
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Astrazeneca Pharmaceuticals Lp paid sponsored hires in similar roles15 certified filings for “Associate Director Oncology Outcomes Research” (Medical Scientists, Except Epidemiologists) in MD: $126k–$185k, median $140k. Most were filed at wage level II (47%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
Or apply yourself on the official page →
Sponsor Radar — Astrazeneca Pharmaceuticals Lp
The US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Astrazeneca Pharmaceuticals Lp →
About the role
Location: Wilmington, Delaware, USA Hybrid: 3 days on site The US Senior Medical Director – Biologics provides US medical leadership for tezepelumab in severe asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, chronic obstructive pulmonary disease, and other disease areas of interest. The role is an integral part of the US Core Medical Team (CMT) and is a primary US medical point of accountability for scientific strategy, evidence generation, and external engagement. This role is ideally suited for a physician or pharmacist with deep expertise in a relevant medical specialty and experience across late-stage development, launch readiness, and post-approval medical excellence. The Senior Medical Director ensures US medical strategy is aligned with global direction while remaining responsive to the healthcare and clinical landscape within the United States. At AstraZeneca, teams work across global boundaries to make an impact and find answers to complex challenges. This role sits at the heart of that mission, combining scientific depth with strategic leadership to advance care in multiple chronic inflammatory diseases. Reporting directly to the US Medical Head of tezepelumab, this leader will guide a high-performing team, drive launches, and influence how evidence, access and clinical practice come together to improve outcomes for patients. Accountabilities: US Medical Strategy & Asset Leadership: • Serve as a US medical lead for tezepelumab activities, accountable for development and execution of the US Brand Medical Plan across pre- and post-approval stages. • Provide strategic medical input to US brand and launch strategy, ensuring alignment of scientific priorities with patient and clinical needs. • Translate complex biology, clinical data, and disease state insights into actionable US medical strategies. Medical Responsibilities: • Lead ongoing post-approval medical strategy to support appropriate scientific exchange and optimize patient care. • Drive Phase 4 and lifecycle management strategy, including real-world evidence (RWE) and effectiveness studies relevant to US clinicians and payers. • Provide medical mentorship for US publication strategy and congress planning; medical review of promotional and non-promotional materials. • US publication management and congress coordination. • Scientific response strategy and data dissemination. • Serve as a medical spokesperson for the US brand as appropriate, supporting external scientific discussions and media inquiries. • Maintain accountability for the evolving US product scientific narrative , incorporating new data, guidelines, and real-world insights. External Engagement & Scientific Exchange (US-focused): • Design and implement a comprehensive US external engagement plan , including: • External Scientific Experts (ESEs) • Academic institutions • Professional societies • Lead planning and participation in national and regional company-led advisory boards • Ensure high-quality, compliant scientific exchange that advances medical knowledge and education. Evidence Generation & Medical Governance: • Collaborate with medical evidence and payer teams to build and implement: • Clinical effectiveness studies • RWE and health outcomes research • Provide medical review and governance for Externally Sponsored Research (ESR) proposals. • Provide medical input into product safety strategy in collaboration with Patient Safety colleagues. • Ensure compliance with all US regulatory requirements , FDA standards, PhRMA Code, and AstraZeneca policies. Internal Collaboration & Capability Building: • Provide clinical education and scientific training for: • US Field Medical organization • Cross-functional partners (commerci