Jobs / United States / Novartis Pharmaceuticals Corporation
Principal Scientist I/II – Hematopoietic Stem Cell & RBC Biology
Novartis Pharmaceuticals Corporation · 🇺🇸 San Diego (California)
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 75 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Novartis Pharmaceuticals Corporation
The US Department of Labor certified 75 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Novartis Pharmaceuticals Corporation →
About the role
Job Description Summary #LI-OnSite Location: San Diego At Novartis, our mission is to reimagine medicine to improve and extend people’s lives. We are seeking a highly motivated Principal Scientist I/II with expertise in sickle cell disease biology, red blood cell physiology, and/or hematopoietic stem cell biology to join our collaborative In Vivo Biology & Pharmacology team. In this role, you will contribute to research programs focused on sickle cell disease while gaining broad exposure to target discovery, pharmacology, translational science, and therapeutic development. Working within a highly collaborative in vivo biology and pharmacology group, you will also have opportunities to support programs across multiple disease areas and therapeutic modalities. This position is well suited for scientists who have recently completed a PhD and/or postdoctoral training, or who are early in their industry careers and eager to apply their disease biology expertise in a dynamic drug discovery environment. The role offers significant opportunities for scientific growth, leadership development, and future people-management responsibilities. Job Description Major accountabilities: • Apply expertise in sickle cell disease, hematopoietic stem cell biology, and RBC pathophysiology to support Global Health research initiatives. • Design, execute, and interpret high-quality biological experiments that inform target discovery, validation, and early drug discovery. • Translate biological insights into actionable hypotheses and therapeutic concepts in collaboration with multidisciplinary project teams. • Take on increasing scientific leadership responsibilities, including mentoring junior scientists and contributing to team development, with opportunities for future people-management growth. • Foster a collaborative, inclusive, and high-performance culture aligned with Novartis Values & Behaviors. • Contribute to project discussions, data reviews, and decision making in a matrixed Biomedical Research environment. • Maintain awareness of external scientific advances and contribute to publications or scientific exchanges as appropriate. • Ensure all work is conducted to the highest standards of scientific rigor, data integrity, safety, and compliance. Minimum requirements • PhD in Molecular Biology, Cell Biology, Immunology, Biochemistry, Microbiology, Virology, Biophysics, Pharmacology, or a related biological science discipline. • Deep expertise in sickle cell disease, red blood cell physiology, and/or hematopoietic stem cell biology, with a strong understanding of hemoglobinopathies. • Strong data interpretation, critical thinking, and scientific communication skills. • Proven ability to independently design experiments, analyze data, and advance scientific questions, as evidenced by high-quality publications, patents, presentations, and/or drug discovery contributions. • Demonstrated behaviors aligned with Novartis Values & Behaviors: Inspired, Curious, Unbossed, and Integrity. Preferred Qualifications • Early-career scientists are encouraged to apply, including recent PhD graduates and postdoctoral fellows seeking to transition into or expand their experience in drug discovery. • Ability to work effectively within multidisciplinary and matrixed environments. • Experience contributing to therapeutic programs from target identification and validation through lead generation and/or early development. • Expertise in assay development utilizing in vitro, ex vivo, and/or in vivo systems. • Prior experience with high-dimensional flow cytometry, including panel design, execution, and data analysis, is preferred. Novartis Compensation and Benefit Summary: The salary for this position is expected to range between $108,500 to $201,