Jobs / United Kingdom / Pfizer INC

Lead Threat Response Operations Analyst

Pfizer INC · 🇬🇧 United Kingdom - Sandwich

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About the role

ROLE SUMMARY Our Global Cyber Defense team is responsible for safeguarding Pfizer's digital assets and infrastructure through proactive threat detection, incident response, and risk mitigation across on-premises, cloud, and hybrid environments. As a Lead Threat Response Operations Analyst within Pfizer’s Global Cyber Defense organization, you will serve as a senior individual contributor, providing technical leadership for the investigation and response to sophisticated cyber threats. While this is not a people-management role, you will lead complex investigations, coordinate the response to security incidents on a global scale, and provide technical guidance to analysts and partner teams. You will bring deep expertise in cyber threat analysis, incident response, malware investigations and adversary tradecraft, with the ability to operate confidently across complex business and technical environments. Working alongside Threat Detection, Digital Forensics, Security Engineering and other partner teams, you will identify, contain and eradicate threats while providing strategic recommendations to strengthen Pfizer’s cyber resilience. ROLE RESPONSIBILITIES • Correlate and analyse security telemetry from endpoint, identity, network, cloud, email and threat intelligence sources to identify, investigate and respond to malicious activity. • Apply knowledge of adversary tactics, techniques and procedures (TTPs) to reconstruct attack lifecycles, determine attack pathways, identify root cause and develop strategic detection and mitigation recommendations. • Lead the assessment of cyber security incidents, determining severity, business impact, threat scope, and appropriate response and escalation actions. • Apply advanced knowledge of networking, operating systems and security architectures to analyse technical evidence, identify attack vectors and guide effective containment, eradication and remediation actions. • Communicate complex technical findings, incident impacts, response decisions and remediation recommendations clearly to technical teams, business stakeholders and senior leadership. • Drive continuous improvement of Threat Response processes, investigation methodologies, operational procedures, reporting standards, and playbooks to enhance the effectiveness and maturity of the cyber incident response capability • Co-ordinate effectively across technical and business teams to coordinate cyber incident response activities, maintaining professionalism and sound judgement during high-pressure situations. • Lead complex cyber security projects and cross-functional workstreams, ensuring timely delivery of objectives and operational improvements. Support the triage of cyber security tickets, providing technical guidance on priority, scope, investigation, escalation and appropriate response actions. • Provide technical guidance, coaching and knowledge sharing to analysts and partner teams to strengthen investigation quality and Threat Response capability. • Participate in a scheduled on-call rotation, including weekends, providing timely response, investigation, escalation, and coordination of cyber security incidents. • Maintain and continuously develop technical expertise in cyber security, threat response, and emerging attack techniques through ongoing training, research, and professional development.   BASIC QUALIFICATIONS • Bachelor’s degree in cyber security, computer forensics, computer science, Information Security, Information Systems, Engineering, Sciences or related field. • Some relevant experience in cyber security operations, incident response or threat investigation, with demonstrated experience leading complex investigations. • Advanced understanding of TCP/IP, network protocols and traffic flows, operati

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Source: Employer career site (Workday) First seen: 2026-10-14 Last confirmed: 2026-10-14 How our data works → Report this job

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