Jobs / Singapore / Astrazeneca Pharmaceuticals Lp
Manufacturing Senior Technician/ Technician
Astrazeneca Pharmaceuticals Lp · 🌍 Singapore
Sponsorship verdict
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
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About the role
Title : Manufacturing Senior Technician/ Technician GCL : C Introduction to role: Be part of history in the making. AstraZeneca is building its first biologics manufacturing campus in Singapore — a groundbreaking USD 1.5 billion investment that will serve as a global hub for innovation and excellence. This innovative facility will deliver end-to-end Antibody-Drug Conjugate (ADC) capabilities with different manufacturing units/buildings in one campus • Small molecule- chemical API production • Large molecule- monoclonal antibody manufacturing • Conjugation • Fill-and-finish operations, including sterile filling and lyophilization • Final secondary packaging The campus will be equipped with modern digital and automation infrastructure, enabling autonomous manufacturing powered by artificial intelligence. In addition, it will be designed for carbon neutrality, embedding sustainability into every aspect of operations and setting a new benchmark for environmentally responsible biologics' manufacturing. We are looking for passionate individuals with relevant experience who thrive in dynamic environments and bring a “make-it-happen” attitude. Joining us means contributing to a project that will not only transform AstraZeneca’s global supply chain but also advance life-changing medicines for patients everywhere. If you’re ready to shape the future of biologics and be part of a once-in-a-generation project, we want you on our team. Accountabilities: • Safe and Compliant Manufacturing: Implement manufacturing activities in accordance with approved electronic batch records, SOPs, permits, cGMP, data-integrity, and Safety, Health and Environmental requirements; operate process equipment and control systems within approved ranges; identify, contain and call out deviations, alarms, unsafe conditions and quality risks; apply appropriate controls for hazardous chemicals, combustible materials, potent compounds and process hazards. • Batch Execution and Equipment Readiness: Achieve manufacturing, quality and delivery goals by verifying equipment status, calibration, materials, labels, utilities and documentation before processing; perform transfers, sampling, cleaning and equipment changeover; complete contemporaneous and accurate manufacturing records and electronic entries to ensure traceability and right-first-time documentation • Shift Coordination and Team Support: Support daily work allocation, production priorities, status reporting and effective shift handovers under the direction of the Shift Team Lead; take responsibility for personal development, build skills in new digital tools and technologies, and collaborate to drive digital adoption within the area. • Quality and Investigation Support: Identify, contain and report process, equipment, documentation or material discrepancies; participate in investigations and root-cause analysis; draft analyses, recommendations and reports; support CAPAs, change controls, risk assessments, validation and inspection readiness while contributing to ongoing change-management. Operational Excellence: Perform first-line troubles-hooting and collaborate with • Quality, Engineering, MS&T and Safety to resolve issues safely and minimize disruption; contribute to continuous improvement using lean and structured problem-solving tools to improve safety, quality, cycle time, yield, waste reduction, equipment reliability and operator effectiveness; support project delivery by analyzing requirements, agreeing action plans, tracking risks and communicating progress. • Operational Readiness and Equipment Qualification: Support operational readiness activities including SOP development, batch record input, equipment setup, line readiness and material flow review; support FAT, SAT, commissioning,