Jobs / Singapore / Astrazeneca Pharmaceuticals Lp
Specialist - MSAT
Astrazeneca Pharmaceuticals Lp · 🌍 Singapore
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
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About the role
Job Title: Specialist - MSAT Career Level: C About Singapore ADC Site: Be part of history in the making. AstraZeneca is building its first biologics manufacturing campus in Singapore — a groundbreaking USD 1.5 billion investment that will serve as a global hub for innovation and excellence. This innovative facility will deliver end-to-end Antibody-Drug Conjugate (ADC) capabilities with different manufacturing units/buildings in one campus: • Small molecule- chemical API production • Large molecule- monoclonal antibody manufacturing • Conjugation • Fill-and-finish operations, including sterile filling and lyophilization • Final secondary packaging The campus will be equipped with innovative digital and automation infrastructure, enabling autonomous manufacturing powered by artificial intelligence. In addition, it will be designed for carbon neutrality, embedding sustainability into every aspect of operations and setting a new benchmark for environmentally responsible biologic's manufacturing. In Manufacturing Science and Technology Team, we are looking for passionate individuals with relevant experience who thrive in dynamic environments and bring a “make-it-happen” attitude. Joining us means contributing to a project that will not only transform AstraZeneca’s global supply chain but also advance life-changing medicines for patients everywhere. If you’re ready to shape the future of biologics and be part of a once-in-a-generation project, we want you on our team. Introduction to role: Are you ready to apply scientific rigor and data-driven insight to strengthen manufacturing processes that deliver life-changing medicines to patients faster? Do you thrive at the intersection of technology transfer, validation, and real-time process monitoring, turning complex data into clear action? As an MSAT Specialist, you will reinforce process robustness across biologics, API, and fill-finish operations, directly shaping consistent product quality and reliable supply. You will drive process validation, control strategy implementation, and continued process verification, using evidence-based decisions to keep our facilities inspection-ready and our product supply on time. Working within a collaborative technology transfer team, you will partner closely with Operations, Quality, Supply Chain, Engineering, and global technical experts. You will help translate new and complex modalities into scalable, compliant manufacturing, using Lean methods and digital tools to accelerate how we deliver therapies with speed and confidence. Accountabilities: • Technology Transfer and Validation: Develop, review, and execute technology transfer plans, validation documentation, risk assessments, control strategies, and lifecycle technical records to enable robust scale-up and scale-out. • Process Control and Monitoring: Implement and maintain control strategies by monitoring critical quality attributes, critical process parameters, and process performance indicators to sustain a state of control. • Data Analytics and Trend Management: Analyze process data and manufacturing trends to identify risks, deviations, and improvement opportunities; call out signals early to protect supply and compliance. • Technical Investigations and CAPA: Lead and contribute to root cause analysis, risk assessments, and implementation of corrective and preventive actions that resolve issues and prevent recurrence. • Regulatory Readiness and Submissions: Prepare technical documentation, data summaries, and responses to support inspections and regulatory filings related to process performance and validation. • Multi-Functional Technical Input: Provide practical guidance across manufacturing and packaging processes to meet internal and external standards while improvin