Medical Director - Skin/IO

Location: Remote with ~40% domestic and international travel Shape the future of cancer care as a Medical Director, Skin/IO at Natera. In this strategic leadership role, you will provide medical expertise and scientific leadership across Natera’s oncology portfolio, with a focus on melanoma, cutaneous malignancies, and immunotherapy applications across solid tumors. You will collaborate with cross-functional teams in research, development, medical affairs, and commercial functions to ensure the scientific integrity and clinical adoption of Natera’s oncology testing solutions. Primary Responsibilities: Clinical Adoption: • Lead the clinical strategy and evidence generation for melanoma, non-melanoma skin cancers, and pan-tumor immunotherapy indications. • Partner closely with clinical development, medical affairs, and commercial teams to translate emerging evidence into meaningful clinical practice applications. • Collaborate with key opinion leaders (KOLs), cooperative groups, and academic investigators to validate and expand clinical use cases for ctDNA-based diagnostics in immuno-oncology. • Provide field-facing education and strategic guidance to healthcare providers, payers, and advocacy organizations on clinical utility, interpretation, and impact of MRD and response monitoring in immune-treated populations. • Identify and address barriers to adoption by aligning evidence generation, messaging, and stakeholder engagement with evolving standards of care and health system needs. Medical Education and Communication: • Serve as the medical and scientific spokesperson for skin and immuno-oncology programs, communicating clinical utility, study data, and product value to external experts and stakeholders. • Partner with commercial teams to develop educational resources, medical content, and scientific training for healthcare providers and internal teams. • Provide scientific leadership during advisory boards, symposia, and investigator meetings. Representation and Advocacy: • Represent Natera at national and international oncology and immunotherapy conferences, fostering relationships with key opinion leaders in melanoma and IO. • Promote a culture of scientific rigor and innovation within the medical affairs and R&D organizations. Research and Development: • Collaborate on clinical trial design, data analysis, and publication strategy related to ctDNA applications in melanoma and other immune-responsive solid tumors. • Identify and cultivate academic and cooperative group partnerships to advance clinical validation and translational research in skin and pan-tumor immuno-oncology. Key Skill Sets / Responsibilities: Skin and Immuno-Oncology Expertise: • Deep clinical knowledge of melanoma and cutaneous oncology, including evolving standards of care, targeted therapy, and checkpoint inhibitor use. • Expertise in immunotherapy mechanisms, response kinetics, and biomarker development across multiple solid tumor types. • Provide expert medical guidance on immunotherapy-specific diagnostic development and clinical implementation. Comprehensive Oncology Knowledge: • Ability to engage across tumor types to support Natera’s broad oncology portfolio. • Maintain awareness of emerging trends in liquid biopsy, precision medicine, and immune response monitoring. Cross-Disciplinary Collaboration: • Work collaboratively with research, development, commercial, and medical affairs to align medical strategy with business objectives. • Partner with regulatory and clinical operations teams to ensure compliance, data quality, and clinical relevance. Qualifications: • MD. or D.O. degree with board certification in Medical Oncology (required). • At least 5 years of experience in oncology, with clinical or research experienc