Jobs / United States / Natera INC
Product Manager, Lab Execution Oncology (Signatera)
Natera INC · 🇺🇸 US Remote · Remote
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 12 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Natera INC paid sponsored hires in similar roles2 certified filings for “Senior Product Manager, Salesforce” (Project Management Specialists) in TX: $104k–$124k, median $114k. Most were filed at wage level III (50%) — 3 lottery entries, ≈46% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Natera INC
The US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 12 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Natera INC →
About the role
Product Manager, Lab Execution Oncology (Signatera) About the Role This is your chance to help build the software that runs Natera's Signatera Plasma lab, a high-throughput lab that processes helps patients achieve and stay in cancer remission . You'll own features and genomics workflows across the lab, from sample intake to sequencing. Every feature you ship makes the lab faster and more reliable, and helps patients and families get answers about their genetic health. Your customers are on the lab floor every day, so you'll see the impact of your work right away. You'll work closely with an engineering team, Lab Operations, R&D, and Automation to turn lab needs into clear requirements and working software. You'll learn the lab inside and out, ask lots of questions, and sweat the details that make Signatera workflows hard, like rework scenarios, process improvements, and task prioritizatioon. You'll bring curiosity, a bias for action, and a willingness to put AI to work so you can move faster and ship smarter. Key Responsibilities Product Ownership • Own features and enhancements for an NGS lab workflow, aligned with the team's roadmap and priorities. • Write clear user stories and acceptance criteria that engineering can execute on. • Create flow diagrams, wireframes, and simple prototypes to clarify requirements with lab and technical teams. • Bring UX design thinking to everything you build, partnering with design to create intuitive workflows that reduce errors and training time on the lab floor. • Groom and prioritize the backlog with your engineering team, balancing new features, bug fixes, and quality-of-life improvements. • Find and close operational gaps on the lab floor, such as sample tracking, primer and control inventory, sample disposition, and instrument availability. • Build robust quality documentation and release notes to enable lab verification and validation. Delivery & Launch • Support new product, panel launches and process improvements, through requirements, UAT, lab process verification and validation, go-live, and hypercare. • Work with Quality and Regulatory to make sure your features meet the requirements of a regulated clinical lab. • Track success metrics such as throughput, turnaround time, failure and rework rates, manual touchpoints, workcell utilization, and adoption for the features you ship. • Gather user feedback after launch and turn it into improvements. Customer & Cross-Functional Collaboration • Partner with Lab Operations, R&D, Automation, and Bioinformatics stakeholders to understand their needs and pain points. • Host in-depth user trainings, feedback sessions, and demos to enable a seamless user experience and feature rollouts. • Work with Automation to integrate software with automated workcells and instruments, including liquid handlers, sample storage, and sequencers. • Spend real time on the lab floor to understand how people actually work, and build deep empathy for lab operators. • Keep stakeholders informed on progress, trade-offs, and risks. • Work with senior product managers and product leadership to grow your skills and contribute to the broader WH/OH strategy. Qualifications Required Skills & Experience • Experience in product management, business analysis, or a related role on software products, ideally in labs, healthcare, or another regulated domain. • Solid skills in writing requirements and user stories. • UX design thinking, with an eye for intuitive, user-centered workflows. • Interest in genomics workflows and the ability to learn complex scientific processes quickly. • Analytical mindset, comfortable using data and dashboards to inform decisions. • Familiarity with Agile (Scrum/Kanban) and tools like Jira and Confluence. • Strong writ