Jobs / United States / Natera INC
Supervisor, Oncology RUO
Natera INC · 🇺🇸 San Carlos, CA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 12 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Natera INC
The US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 12 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Natera INC →
About the role
POSITION SUMMARY: Join Natera’s Oncology Research Use Only (RUO) team as a Supervisor for the Signatera Plasma Team. You will direct laboratory staff executing cell-free DNA (cfDNA) extraction, library preparation, and Next-Generation Sequencing (NGS) workflows to advance our personalized Minimal Residual Disease (MRD) assays. Every sample represents a real person, and you will ensure that all lab processes operate with the pace and precision required to support our clinical pipeline. PRIMARY RESPONSIBILITIES: • Oversee the daily scheduling of employees executing DNA extractions, library preparation, Nucleic Acid Quality Control (QC), and NGS workflows • Conduct regular 1:1 meetings to deliver unvarnished, data-backed performance evaluations and guide career development • Take ownership of daily lab operations by directly executing sample processing alongside the team to maintain throughput • Serve as the primary technical point of contact, using data to guide team members on data interpretation, next steps, and troubleshooting • Execute process development and method/instrument testing to increase operational precision and scale • Use data to identify lab process deviations, root-cause the underlying issues, and document findings via nonconformance reports to drive corrective action • Draft, generate, and rigorously review Standard Operating Procedures (SOPs) and work instructions • Maintain precise records of lab work using Google Sheets, Microsoft Excel, and internal Laboratory Information Management Systems (LIMS) • Ensure accurate, ethical, and appropriate management of samples in strict compliance with all applicable federal regulations • Think team by partnering directly with Oncology RUO peer groups to eliminate bottlenecks and optimize sample processing without needing translation layers • Present data-backed summaries on team activities, project milestones, and timeline adherence • Adapt to evolving science and operational needs, taking ownership of tasks that move the work forward without waiting for a finished playbook • Handle protected health information (PHI) in paper and electronic formats as required to perform duties • Complete required HIPAA/PHI privacy and security training within the first 30 days of hire and maintain current status on all training QUALIFICATIONS: • BS/BA in a biological science or equivalent • 3 to 4 years of related laboratory experience • Prior team management experience is highly preferred • Must pass a post-offer criminal background check KNOWLEDGE, SKILLS, AND ABILITIES: • Direct hands-on experience with nucleic acid techniques, including isolation, purification, quantification, amplification, and hybridization capture • Extensive familiarity with rigorous pipetting practices using single- and multi-channel micropipettes and serological pipettes • Hands-on experience operating Laboratory Automation platforms (e.g., Hamilton, Tecan, Biomek, QIAsymphony) • Hands-on experience with library preparation and NGS platforms • Proficiency with LIMS and database software • Proficiency with Microsoft Office and Google Workspace applications • Experience leading a lab team, spanning scheduling, training, workload prioritization, and building an execution-focused culture, is a plus • Ability to think analytically, testing assumptions with data to troubleshoot and solve complex problems • Clear, direct oral and written communication skills to present data and identify operational improvements • Demonstrated interpersonal skills to build effective working relationships within the functional area • Manage competing priorities while operating with pace and precision in an evolving scientific environment PHYSICAL DEMANDS AND WORK ENVIRONMENT: • Duties are typically perfo