Manager, Inventory and Operations Accounting

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: The Manager, Inventory and Operations Accounting role will help manage Vaxcyte’s cost accounting functions, including standard costing, inventory valuation, and manufacturing variance analysis. This role also owns the full manufacturing accrual process for the Manufacturing Accounting Team — maintaining accrual trackers, preparing monthly accrual journal entries, reconciling manufacturing general ledger accounts, and preparing manufacturing flux analysis. The Manager, Inventory and Operations Accounting role partners closely with Supply Chain and FP&A to ensure accurate cost data, drive margin improvement initiatives, and maintain strong internal controls over inventory and cost of goods sold (COGS). The ideal candidate combines strong technical accounting skills with the ability to translate cost data into actionable business insights. Essential Functions: • Maintain and update standard costs for materials, labor, and overhead. • Analyze and report on man ufacturing variances (purchase price, usage, labor, and overhead) and partner with Supply Chain to explain and resolve root causes. • Own the man ufacturing accrual process end to end, including maintaining accrual trackers by key vendors. • Prepare monthly accruals for man ufacturing vendors, ensuring costs are recorded in the appropriate period . • Prepare journal entries related to man ufacturing accruals, inventory, COGS, and man ufacturing variances. • Man a g e inventory valuation, reserves, scrap and obsolescence, and reconciliation processes across all locations. • Reconcile man ufacturing and cost-related general ledger accounts and ensure timely , accurate month-end close. • Prepare monthly and quarterly flux analysis for inventory, COGS and man ufacturing accrual accounts. • M aintain and execute internal controls over inventory, standard costing, COGS and man ufacturing accrual s in compliance with GAAP and Sarbanes-Oxley (SOX). • Support quarterly external audits and SOX testing related to man ufacturing, inventory, and cost accounting; man a g e requests, remediate deficiencies, and track corrective action plans. • Investigate and resolve discrepancies identified in physical inventory counts and cycle counts. • Support ERP and system enhancements related to inventory and cost accounting. • Additional tasks and responsibilities as assigned. Requirements: • Bachelor’s degree in Accounting , Finance, or related field. • 7 + years of progressive cost accounting experience in a biotech man ufactu