Senior Manager, Manufacturing Systems & Operations Readiness (Contractor)

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: As Vaxcyte’s products progress toward late-stage development and commercialization, the Manufacturing organization requires robust digital tools, structured project tracking, and disciplined readiness oversight to support commercial launch preparation and routine GMP manufacturing. This position will support the Manufacturing organization by developing, maintaining, and driving Smartsheet-based trackers, dashboards, action logs, and gap-assessment tools that enable clear visibility into commercial readiness, documentation status, manufacturing campaign preparation, risks, dependencies, and cross-functional deliverables. Working closely across the Manufacturing team, MSAT, Process Development, Supply Chain, Quality, Regulatory, Project Management, Business Development, and multiple CDMOs/CMOs, this position will help establish structure, transparency, and governance across operational readiness activities. The role will be accountable for supporting readiness gap assessments, tracking closure of actions, consolidating input from stakeholders, monitoring document and campaign readiness, supporting organizational maturation, and preparing clear status updates for Manufacturing leadership. In addition, the role will provide direct support to the Head of Manufacturing with meeting administration, governance routines, team event coordination, and follow-up management. The ideal candidate will combine strong project tracking and digital tool capabilities, particularly Smartsheet, with an understanding of GMP manufacturing operations, commercial readiness, organizational effectiveness, and cross-functional collaboration in a biologics or vaccine manufacturing environment. This position will report to the Executive Director Manufacturing of Vaxcyte Switzerland. Ideal Candidate Profile: The ideal candidate is a highly structured manufacturing systems and operations enablement professional with experience in GMP biotech or pharma environments, preferably biologics, vaccines, or external manufacturing. This person does not need to be a deep technical manufacturing expert, but must understand manufacturing operations, documentation, campaign readiness, and CMO/CDMO interfaces well enough to create clarity, structure, visibility, and follow-through across complex cross-functional work. The strongest candidate will be highly skilled in Smartsheet and digital project tracking, able to build dashboards, trackers, action logs, readiness heatmaps, and reporting tools that translate comple