Investment & Portfolio Manager

Business Introduction GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver £40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines. Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges. Job Purpose  The Investment & Portfolio Manager runs the enterprise portfolio governance and planning cycle for DPTF. The role operates the prioritisation framework set by the Director, Planning & Performance. It structures incoming demand, checks that business cases are complete and evidenced,applying investment-appraisal discipline before they reach a funding decision, facilitates the forums in which platform and domain leads prioritise and commit, and provides transparency of demand, investment and roadmap across the function. The enterprise portfolio is assembled from the domain portfolios, so the federated Domain Portfolio Managers are the role's primary working relationship. It aggregates their portfolios into a single enterprise view and aligns their planning cycles and standards to it. Prioritisation decisions rest with platform and product domain leadership. This role ensures the process is followed, the inputs are complete, the alternatives are comparable and the decisions are recorded and acted on. Key Responsibilities •        Operate the enterprise portfolio governance process for DPTF, running the intake, assessment and approval route through which technology demand enters the portfolio. •        Coordinate and facilitate the quarterly planning cycle, working through the federated Domain Portfolio Managers so that domain planning feeds the enterprise cycle to a common timetable, and ensuring platform and domain leads arrive with the information needed to prioritise. •        Structure and analyse incoming demand against the agreed prioritisation criteria of value, risk, capacity, strategic fit and OKR alignment, presenting it in a form that supports comparison. •        Run business case governance, checking that proposals carry credible scope, cost profiles, delivery estimates and benefit profiles before they reach a funding decision. •        Collect the inputs required for prioritisation from business stakeholders and platform and domain leadership, following up on gaps and challenging quality against the agreed standard. •        Facilitate portfolio governance forums and steering cadences, ensuring decisions, owners and follow-up actions are documented and closed out to deadline. •        Maintain the integrated portfolio roadmap across products, platforms and programmes, working with the federated Domain Portfolio Managers to surface and resolve cross-domain dependencies and to flag where changes in demand or capacity require re-prioritisation. •        Provide portfolio transparency and reporting on demand, investment commitment, delivery progress and dependency risk to the Director, Planning & Performance and to DPTF leadership. •        Act as the central point of liaison for the federated Domain Portfolio Managers, aggregating the domain portfolios into the enterprise view, translating central standards into what each domain applies, and ensuring portfolio data is complete, consistent and comparable across domains. •        Maintain the portfolio RAID position, esc