Research Technician II

Union:  Non-Union Number of Vacancies:  1 New or Replacement Position: Replacement  Site:  Princess Margaret Cancer Centre Department:  Princess Margaret Genomics Centre Reports to:  Principal Investigator  Salary Range: $61,854 - $77,318 per annum Hours:  37.5 hours per week Shifts:  Monday - Friday  Status:  Permanent Full-time Closing Date: November 13, 2026 Position Summary  The Princess Margaret Genomics Centre is seeking a Permanent Full-time Research Technician II, with potential for advancement within the PMGC team. As an integral member at the Genomics Centre, a core facility, the research technician must be dedicated and result-driven and will be involved in all aspects of service projects, following SOPs and meeting target deadlines. this role resides in our bulk genomics services team. Duties Working under the direction of senior staff, the successful applicant will utilize SOPs to: • Perform genomics library preparation (RNA, whole genome, exome) • This includes QC of input material (RNA and DNA), following SOPs for construction, and QC of final products for internally constructed and externally submitted sequencing-ready libraries • Onboarding of samples from and communication with clients • DNA epigenetic profiling (methylation) library construction • Input sample QC by BioAnalyzer, Nanodrop, and fluorimetry • Final library QC by BioAnalyzer • Entry of sample and library information into LIMS • Illumina NovaSeq X Plus loading and operation • At minimum, Bachelor’ degree in Genomics, Molecular biology or related discipline is required,  • At least three (3) years of hands-on related experience required  • At least one (1) year of experience with standard molecular biology laboratory techniques, such as: • PCR reaction set up and purification • qPCR reaction assembly and data interpretation  • Nucleic acid quantification by spectrophotometry and fluorimetry • Sequencing library construction, an asset  • Experience with using LIMS (Laboratory Information Management System) is an asset • Experience with Illumina DNA sequencing library construction workflows and instrument operation is an asset  • A willingness to learn new techniques and technologies is required • Excellent organizational and time management skills is required • Ability to work independently and accurately under deadlines is required • Excellent interpersonal and communication skills in a team environment is required Why join UHN? In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN. • Competitive offer packages • Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/ ) • Close access to Transit and UHN shuttle service • A flexible work environment • Opportunities for development and promotions within a large organization • Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.) Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration. All applications must be submitted before the posting close date. UHN uses email to communicate with selected candidates.  Please ensure you check your email regularly. At University Health Network (UHN), artificial intelligence technologies may be used to assist in the screeni