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The company's headquarters is not the same as where you may work from. Visa sponsorship only matters if you would relocate; see below.
Visa sponsorship, if you would relocate
Sponsorship verdict
Sponsorship possible
One solid signal, not two. Worth applying, and worth asking about sponsorship early.
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✓
Employer is on a government sponsor recordThe US Department of Labor certified 1 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Apr 2026) — the step every H-1B hire needs first.
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The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
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No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area.
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✓
What Iovance Biotherapeutics INC paid sponsored hires in similar roles1 certified filing for “Director, IT Infrastructure and Operations” (Software Developers) in CA: $258k–$258k, median $258k.
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Confirmed live todayWhen a source last listed this job as open.
Details and sources
- Employer is on a government sponsor record
- The US Department of Labor certified 1 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Apr 2026) — the step every H-1B hire needs first. Source: LCA disclosure data (US Department of Labor (OFLC)).
- No salary bar for this route
- H-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Iovance Biotherapeutics INC paid sponsored hires in similar roles
- 1 certified filing for “Director, IT Infrastructure and Operations” (Software Developers) in CA: $258k–$258k, median $258k. Most were filed at wage level IV (100%) — 4 lottery entries, ≈61% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence. It is not legal advice and never a guarantee: the employer and the immigration authority decide. Sign in to factor in where you can already work.
About the role
About Iovance Biotherapeutics, Inc.
Iovance Biotherapeutics , Inc. is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to serve thousands of cancer patients worldwide each year. For more information, please visit www.iovance.com .
Amtagvi® and its accompanying design marks, Proleukin ® , Iovance ® , and IovanceCares™ are trademarks and registered trademarks of Iovance Biotherapeutics, Inc. or its subsidiaries. All other trademarks and registered trademarks are the property of their respective owners.
Information on Iovance’s broad, industry-leading patent portfolio is available on the Intellectual Property page on www.iovance.com .
Overview
The Senior Cellular Therapy Medical Director reports to the Executive Scientific Director, Medical Affairs, and represents Iovance Medical Affairs as needed, serving as a TIL cell therapy therapeutic area expert in educational, strategic, and tactical discussions and presentations with internal colleagues and external experts and investigators. This role requires strong clinical expertise and credibility, recent surgical and/or cell therapy experience, and the ability to partner effectively with healthcare providers to apply practical insights to patient care, including perioperative workflows and tumor procurement. The Senior Cellular Therapy Medical Director also collaborates with internal cross-functional teams to ensure territory alignment and optimization, and to support medical strategies in line with overarching corporate objectives.
Essential Functions and Responsibilities
• Support and educate providers to optimize tumor tissue starting material for lifileucel manufacturing
• Lead engagement and best-practice discussions with surgeons on tumor tissue procurement
• Support ATC medical onboarding to prepare for direct patient care, and serve as an ongoing resource for patient- and product-specific questions
• Serve as subject matter expert and clinical support for TIL cell therapy
• Provide clinical trial support by engaging surgeons across all Iovance trials and investigator-sponsored trials (ISTs)
• Represent Iovance Medical Affairs as a TIL cell therapy expert across internal and external venues, including US and Global cross-functional teams, clinical sub-teams, external consultants, and advisory boards and steering committees.
• Work cross-functionally to support Commercial Quality, Market Access, Clinical Development, and the broader Med Affairs team.
• Participate in various Medical Affairs cross-functional working groups.
• Represent Iovance at professional meetings, congresses, and local symposia.
• Provide high-quality clinical input and review of disease strategy plans, slides, manuscripts, educational materials, IIT protocols, steering committee and advisory board meeting objectives, Standard Response Letters, and Commercial brand plans.
• Partner with Scientific Communications to develop timely publication strategies and plan, gap analysis, and key messages.
• Interact with key stakeholders
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