Skills this job asks for
LeadershipProduct managementLean / Six Sigma
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Where you can work from
United States only
Based on the listing's location: US Remote.
The company's headquarters is not the same as where you may work from. Visa sponsorship only matters if you would relocate; see below.
Visa sponsorship, if you would relocate
Sponsorship verdict
Sponsorship possible
One solid signal, not two. Worth applying, and worth asking about sponsorship early.
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✓
Employer is on a government sponsor recordThe US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first.
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The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
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No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area.
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✓
What Natera INC paid sponsored hires in similar roles1 certified filing for “Manager, Clinical Data Software Management” (Software Developers) in NC: $135k–$135k, median $135k.
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Confirmed live todayWhen a source last listed this job as open.
Details and sources
- Employer is on a government sponsor record
- The US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. Source: LCA disclosure data (US Department of Labor (OFLC)).
- No salary bar for this route
- H-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Natera INC paid sponsored hires in similar roles
- 1 certified filing for “Manager, Clinical Data Software Management” (Software Developers) in NC: $135k–$135k, median $135k. Most were filed at wage level III (100%) — 3 lottery entries, ≈46% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence. It is not legal advice and never a guarantee: the employer and the immigration authority decide. Sign in to factor in where you can already work.
About the role
Senior Manager, Software Engineering — Case Management Platform
POSITION TITLE: Senior Manager, Software Engineering — Case Management Platform (CMP)
POSITION LOCATION: San Carlos, CA, Austin, TX, or Remote, USA
POSITION SUMMARY
Natera is seeking a hands-on, technically deep Senior Manager of Software Engineering to lead our Case Management Platform (CMP) Core team. CMP is the technical backbone that moves patient cases from order to result across Natera's oncology, women's health, and organ health product lines — software whose reliability translates directly into turnaround time, lab efficiency, and patient outcomes.
This is explicitly not a people-management-only role. You will integration into an existing platform application department and build a new high leverage squad with a distinct mission to bridge Natera's commerce and fulfillment domains. With a small initial footprint, you are expected to be in the code: setting architectural direction, writing and reviewing code, driving production support, and modeling the engineering standard. As the team grows, you will rebalance your time toward leadership, hiring, and strategy — but hands-on technical credibility is a permanent requirement of this role.
We are looking for an agent of change. CMP is pushing hard on AI-native ways of working, mission-based team structure, and InnerSource stewardship. You will not just adopt these shifts — you will drive them.
RESPONSIBILITIES
Lead technically
• Set and defend the architectural direction for your scope; make the hard trade-off calls and own the outcomes
• Write production code, review PRs, and participate in production incident response alongside the team
• Drive design reviews; raise the technical bar through example, not memo
• Own the full SDLC for your systems — conception, design, implementation, test, release, operation, and sunset
Manage and grow people
• Hire and develop top performers; recruit for attitude as aggressively as for aptitude
• Hold regular 1:1s, deliver direct feedback with radical candor, and address underperformance quickly and respectfully
• Guide career development; create real ownership opportunities and delegate decisions, not just tasks
• Build a diverse, high-trust team that reflects the users and patients we serve
Drive the AI-native transformation
• Treat AI as core to how the team builds, delivers, and operates — not an experiment on the side
• Champion the adoption of AI coding tools, agent orchestration, and AI-assisted operations across your team and influence peer teams to follow
• Measure and communicate the leverage AI is creating in your org; retire practices that no longer earn their keep
Partner across the business
• Act as the primary technical point of contact for product management, commerce stakeholders, lab operations, and adjacent engineering teams
• Build and maintain a working relationship with lab managers, lab supervisors, and commerce leaders — understand their world firsthand
• Translate business priorities into engineering plans and translate engineering realities into options business leaders can act on
Manage delivery
• Own estimates, scope, dependencies, risks, and delivery for your team's commitments
• Run lean, outcome-oriented ceremonies; prefer visible work and short feedback loops over heavy process
• Facilitate collaboration and remove blockers; escalate honestly and early
Effect change
• Lead the evolution of our ways of working
• Propose and drive improvements beyond the walls of your immediate team
QUALIFICATIONS
• BS or MS in Computer Science or equivalent experience
• 8+ years of professional software development experience, with meaningful time building complex data or process-management applications
• 3+ years leading enginee
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