Skills this job asks for
CompliancePythonCommunicationSQLExcel
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Sponsorship verdict
Sponsorship possible
One solid signal, not two. Worth applying, and worth asking about sponsorship early.
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✓
Employer is on a government sponsor recordThe US Department of Labor certified 9 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest May 2026) — the step every H-1B hire needs first.
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The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
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No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area.
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✓
What Billiontoone INC paid sponsored hires in similar roles3 certified filings for “Associate Bioinformatics Engineer” (Molecular and Cellular Biologists) in CA: $111k–$143k, median $113k.
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Confirmed live todayWhen a source last listed this job as open.
Details and sources
- Employer is on a government sponsor record
- The US Department of Labor certified 9 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest May 2026) — the step every H-1B hire needs first. Source: LCA disclosure data (US Department of Labor (OFLC)).
- No salary bar for this route
- H-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Billiontoone INC paid sponsored hires in similar roles
- 3 certified filings for “Associate Bioinformatics Engineer” (Molecular and Cellular Biologists) in CA: $111k–$143k, median $113k. Most were filed at wage level I (33%) — 1 lottery entry, ≈15% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence. It is not legal advice and never a guarantee: the employer and the immigration authority decide. Sign in to factor in where you can already work.
About the role
A Rare Opportunity to Shape the Future of Genomics
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are looking for a Senior LIMS Engineer to join our Laboratory Information Management System (LIMS) team in support of clinical patient testing in our high-throughput CLIA lab. The Sr. LIMS Engineer will be responsible for (1) Deepening integration between existing BTO software and our clinical LIMS, (2) taking ownership of critical portions of the LIMS sample processing pipeline, and (3) maintaining, improving, and building LIMS applications, tools, and infrastructure.
This role will help to build upon the strong technology and execution found at BTO. This is considered an onsite role at our Union City lab, with flexibility to work from home or at our Menlo Park site when applicable.
Responsibilities:
• Develop modern, user-friendly, secure software for our clinical lab
• Solve complex issues in sample handling, automations, or infrastructure affecting lab processing
• Work as a part of cross-functional teams to gather requirements, facilitate user acceptance testing, iterate on feedback, file quality system paperwork, and launch products
• Work independently and prioritize projects based on company goals
• Mentor junior LIMS engineers and technical members of other teams in best practices
• Participate in performing LIMS code reviews, verifications, and validations
• Ensure compliance to all relevant corporate and regulatory requirements
Requirements:
• Bachelor's degree with Biological or Computational focus
• Experience with both Python and AI-assisted development
• 5+ Years experience with developing LIMS, apps, or customer-facing tools
• Ability to troubleshoot and diagnose advanced technical issues
• Experience developing scripting solutions to automation problems
• Strong attention to detail and ability to work flexibly and well under accelerated timeframes
• Highly organized, strong written and verbal communication skills
• Creative problem-solver who enjoys a variety of daily tasks
Nice-To-Haves:
• Experience working in CLIA Lab, medical device, or pharma
• Experience with data analysis using Python, SQL, or Excel
• Familiarity with Quality Management Systems and related regulations (CFR 21 Part 11, ISO 13485, etc)
Benefits And Perks:
• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid a
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