mRNA Analytical Development Senior Scientist

Job title : mRNA Analytical Development Senior Scientist • Location: Waltham, MA About the job In order to strengthen the Biochemical and Biophysical group in R&D Analytical Sciences Department, Sanofi Pasteur is looking for a skilled and highly motivated individual to develop novel methods and improve characterization of mRNA vaccines in development by working closely with the bioprocess development group. Analytical Sciences Department has the overall responsibility to develop, qualify and validate robust analytical methods to support release and characterization testing of mRNA Drug Substances and Drug Products candidates in development.   Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization.​ About Sanofi: We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world and are supported and enhanced through our diverse portfolio of medical device and diagnostic products. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities: • Develop advanced technology for biochemical, biophysical, and bioassay assay development in support of mRNA vaccine process and product development, product release, stability, and comparability study. • Work with analytical leads supporting CMC activities.   • Write and review method documentation and characterization reports in support of regulatory filings. • Ensure timely completion of assignments and deliverables. Independently design and execute complex experiments.  Author method development and investigation reports. • Manage assay testing at CROs if required, support investigation, deviation, and change control. • Participate internal non-GMP and GMP lab set up and product release and stability testing. • Supervise and train junior scientists. • Compliant to Sanofi Quality standards and HSE policy. Participate in continuous improvement of laboratory safety and quality compliance. About you Basic Qualifications • PhD or Master's Degree in Biochemistry, Biology, Cell Biology, Analytical Chemistry, Biotechnology or related sciences. • Ph.D. with a minimum of 3 years of experience in the pharmaceutical or biotechnology industry, or a Master's degree with a minimum of 6 years of experience in the pharmaceutical or biotechnology industry. • Previous CMC analytical development experience. • Expertise in LC (RP, IEX, SEC, HILIC) and one or more of the following techniques but not limited to CGE, spectroscopy, particle analysis. • Ability to perform complex method development and propose appropriate method improvement suitable for CMC space. Preferred • Knowledge of nucleic acid/oligonucleotides chemistry and standard analytical methods of these molecules. • LC-MS experience. • Hands on experience in quality control laboratory environment is a plus. Why choose us? • Bring the miracles of science to life alongside a supportive, future-focused team. • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. • Be part of a