Senior Manager MES Infrastructure

About the Team: Enterprise Systems is the backbone of GSK’s internal operations in Digital & Tech, enabling GSK Global Functions teams such as Finance, Procurement, HR, Legal, Compliance, WREF (Workplace & Real Estate Facilities), CGA (Communications & Government Affairs) and Corporate Secretariat to run seamlessly. This team designs and delivers cutting-edge digital platforms that power critical processes, ensuring efficiency, compliance, and scalability across the enterprise. Enterprise Systems Management & Business Operations delivers digital solutions that support Enterprise Systems running as a high-performing organisation. This team drives financial discipline, operational rigour and strategic alignment across the ES (Enterprise Systems) portfolio that safeguard GSK’s integrity and reputation globally. By joining this team, you’ll help shape systems that support thousands of employees worldwide, driving innovation and reliability in the tools that keep GSK moving forward. Job Purpose: The Senior Manager MES Infrastructure Engineer is responsible for providing secure, reliable, and standardized MES development, testing, deployment, and production environments across Siemens OpCenter, Emerson Syncade, Mendix, and AspenTech MES platforms. The role manages engineering tools, environments, automation, CI/CD (Continuous Integration / Continuous Deployment) processes, deployment standards, and technical controls to support efficient and compliant MES solution delivery. Working closely with development, architecture, infrastructure, cybersecurity, OT (Operational Technology), and quality teams, the role ensures MES platforms, environments, and deployment processes are scalable, secure, compliant, and aligned with enterprise standards. The role also drives standardization, automation, reuse, and (Artificial Intelligence) AI-enabled engineering capabilities while maintaining appropriate security, governance, and traceability. The MES Infrastructure Engineer is accountable for the MES engineering platform and deployment ecosystem but does not own product strategy, solution architecture, or development delivery. Use AI-assisted engineering as the primary approach for configuring, automating, testing, documenting, and supporting MES infrastructure solutions. Deliver secure, reliable, and compliant infrastructure services that support MES platform performance, availability, and manufacturing operations.  Key Responsibilities: • Design, build, own, and continuously improve MES infrastructure platforms, environments, CI/CD pipelines, and deployment automation for Syncade, OpCenter, Mendix, and AspenTech MES using version-controlled Infrastructure as Code (IaC) and automation frameworks.  • Own the design of MES platform, environment, and pipeline architectures within approved enterprise standards, documenting technical decisions, reusable patterns, and implementation approaches.  • Develop and maintain automated build, test, deployment, monitoring, backup, recovery, and configuration management processes to improve platform reliability, scalability, and consistency.  • Provide MES developers and site teams with standardized environments, self-service capabilities, automation tools, and engineering frameworks that improve delivery efficiency and consistency.  • Coordinate software releases and environment promotions, ensuring traceability, validation, quality, security, and GxP (Good Practice) compliance requirements are met.  • Lead validation activities for infrastructure and platform changes, including risk assessments, testing, documentation, compliance evidence, and release readiness.  • Apply AI-assisted engineering practices to improve productivity and solution quality, ensuring all AI-generated outputs are reviewed, valida