Jobs / United States / Pfizer INC
Postdoctoral Research Fellow, BioMedicine Design
Pfizer INC · 🇺🇸 United States - California - San Diego
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 40 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 9 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Pfizer INC paid sponsored hires in similar roles2 certified filings for “Postdoctoral Fellow, Biophysics Small Molecule Discovery” (Biochemists and Biophysicists) in CA: $90k–$135k, median $113k. Most were filed at wage level I (50%) — 1 lottery entry, ≈15% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Pfizer INC
The US Department of Labor certified 40 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 9 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Pfizer INC →
About the role
Last day to apply: Oct. 13th, 2026 *Must include two letters of recommendation, one from your PI, and 1 from an additional professor. BioMedicine Design (BMD) group at La Jolla, CA is seeking a highly driven and innovative Ph.D.-level scientist to join our Biotherapeutics Discovery group as a Postdoctoral Research Fellow in driving therapeutic innovation through the development of a next-generation T cell engager (TCE) designed to improve tumor selectivity and minimize on-target, off-tumor toxicity. This is a unique opportunity to be trained at the interface of protein engineering, cell biology, and immunology, to work collaboratively with diverse research teams within Pfizer, and to publish in high-impact journals. By the end of the program, the Postdoc will be proficient in antibody discovery and engineering, cellular assays, and preclinical evaluation, and will be fully prepared to contribute to early-stage therapeutic discovery and modality selection. The ideal candidate should have solid training in molecular biology, cell biology, immunology or structural biology, with a good understanding of biology/oncology. Key Responsibilities: • Demonstrate strong technical and scientific rigor in project planning and gap identification • Proactively conduct literature searches to gather relevant information and form hypotheses for testing experimentally • Design and produce constructs to further our understanding of underlying biology and mechanism of action; develop and utilize cell-based assays to test hypothesis and screen and rank molecules • Generate and effectively communicate results regularly at internal meetings, make data-driven decisions in shaping direction of research project • Participate in developing creative approaches to discover and optimize therapeutics BASIC QUALIFICATIONS (must-have): • PhD in cancel biology, immunology, molecular or cellular biology, biochemistry, chemical and biomolecular engineering or a related discipline is required • Provide two letters of recommendation with your application (e.g. professors/PI) • Willingness to commit to the fixed‑term full-time postdoctoral fellowship (duration: 2–4 years) • Less than 2 years post-doctoral experience • At least 1 first-author scientific research article in high-quality specialty or general readership journals • Technically proficient in (at least) some molecular and cell biology tools, including construct design, molecular cloning, recombinant protein expression/purification, mammalian cell culture and cell line engineering, cell line transfection and characterization, development of cell-based assays (e.g. cytotoxicity proliferation, cytokine production), and flow cytometry • Proficient with data reporting and analysis software, strong planning and organizational skills • Strong motivation, passion and commitment to science and engineering of novel entities • Ability and desire to multitask and work in a fast-paced, interdisciplinary scientific team both independently and as part of a team, strong problem-solving and analytical skills • Excellent written and oral communication skills PREFERRED QUALIFICATIONS (nice-to-have): • Prior experience with antibody discovery, protein engineering, and/or display technology (e.g., yeast and/or phage display) is highly desirable • Experience with bispecific antibodies or T cell engagers ADDITIONAL INFORAMATION Work Location Assignment: On Premise Last day to apply Oct. 13th, 2026 The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead he