Jobs / United States / Sanofi US Services INC
Senior Principal Scientist, Type 2 Immunology
Sanofi US Services INC · 🇺🇸 Cambridge, MA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 47 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 29 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Sanofi US Services INC paid sponsored hires in similar roles6 certified filings for “Senior Scientist” (Biochemists and Biophysicists) in MA: $100k–$122k, median $101k. Most were filed at wage level I (50%) — 1 lottery entry, ≈15% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
Or apply yourself on the official page →
Sponsor Radar — Sanofi US Services INC
The US Department of Labor certified 47 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 29 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Sanofi US Services INC →
About the role
Job title: Senior Principal Scientist Type 2 Immunology Location: Cambridge, MA About the Job Immunology and Inflammation Therapeutic Area We have an exciting opportunity to join Sanofi's Translational Biology team as a Senior Principal Scientist within the Type 2 Immunology cluster. This role sits at the intersection of cutting-edge preclinical research and clinical development, offering a unique platform to shape the trajectory of one of the industry's most compelling immunology portfolios. Working at our Cambridge Crossing research campus, you will contribute to a team with deep commitment to scientific excellence and patient impact across dermatology, gastroenterology, respiratory, and rheumatology. This position carries a dual mandate. Leading preclinical research programs from hypothesis generation through execution, while also serving as to support early clinical and/or late-stage or marketed product programs. In this capacity, you will drive translational research strategies that inform clinical development and support lifecycle management initiatives for assets. You will integrate insights from clinical studies back into research strategy, ensuring a continuous and productive dialogue between both early research, clinical development and medical affairs. The successful candidate will leverage Sanofi's extensive technical capabilities, including AI enabled platforms, single cell technologies, and multiomic approaches, while collaborating closely with Development, Medical Affairs, and Commercial teams. This is an opportunity to make a meaningful scientific and strategic contribution within a highly collaborative, cross functional environment. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities • Lead preclinical research programs from hypothesis generation through experimental execution, integrating findings into broader clinical strategy. • Directly support early clinical and or late stage or marketed product programs, translating clinical insights back to research and driving translational strategies to support clinical decision making and asset life cycle management. • Design and execute research programs in close partnership with Development, Medical Affairs, and Commercial teams as part of IEGP to maximize the value of Sanofi's portfolio. • Independently formulate research hypotheses and apply scientific expertise to design and execute experiments using murine and human immunology approaches. • Develop novel in vitro and in vivo assays and apply advanced technologies including single cell approaches (flow cytometry, scRNAseq), multiomics, and imaging platforms. • Lead cross functional collaborations and manage stakeholder relationships effectively across a matrixed global organization. • Communicate research findings clearly and compellingly to diverse audiences, both technical and nontechnical, internal and external. • Mentor and actively support the scientific and professional development of junior team members. • Stay at the forefront of scientific advances and contribute to the strategic direction of the group. • Maintain laboratory activity while providing scientific leadership; this role has an expectation of bench engagement as necessary. • Ensure adhere