Jobs / United States / Regeneron Pharmaceuticals INC
Principal Toxicologist
Regeneron Pharmaceuticals INC · 🇺🇸 TARRYTOWN
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 290 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 40 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Regeneron Pharmaceuticals INC
The US Department of Labor certified 290 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 40 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Regeneron Pharmaceuticals INC →
About the role
Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal Toxicologist to join our Toxicology group within Drug Safety and Pharmacometrics, applying scientific and regulatory expertise to lead nonclinical development programs with minimal supervision. You'll have a deep understanding of global regulatory guidelines to ensure all aspects of nonclinical safety are met, enabling progression of assigned programs across the life cycle of a therapeutic asset. You'll manage all aspects of multiple programs across therapeutic classes, demonstrating the ability to prioritize and meet deadlines with high-quality deliverables, and will work in collaboration with other members of the toxicology group to develop policies and procedures related to the conduct of toxicology research at Regeneron. Candidates with experience across diverse therapeutic modalities, such as monoclonal antibodies, oligonucleotides, and gene therapies, are preferred. Prior experience providing toxicology and nonclinical safety support for Ophthalmology, Oncology, and/or Infectious Diseases programs is a plus. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide. When & where: • Location: On-site in Tarrytown, NY Discover your role: • Represents toxicology on global research and development project teams, communicating non-clinical safety strategy • Develops regulatory risk assessment strategies and contributes to program planning, budgeting, and the execution of toxicology studies to support regulatory and clinical development milestones • Collaborates with cross-functional subject matter experts to design and execute nonclinical safety programs that support drug development and clinical advancement • Provides scientific oversight of CRO activities, including study design, conduct, monitoring, data interpretation, and reporting • Communicates nonclinical safety data, risk assessments, and development strategies to internal and external stakeholders, including regulatory agencies • Authors and reviews nonclinical safety content for global regulatory submissions and provides toxicology expertise in interactions with health authorities • Collaborates with external partners and consultants to advance nonclinical safety strategies and support drug development programs • Maintains currency with GLP regulations and ICH, FDA, and EMEA non-clinical safety guidelines • Keeps up with the latest scientific developments by reading current literature and attending conferences • Drives continuous improvement initiatives and mentors junior scientists to promote scientific excellence and professional development This role requires: • Advanced Degree (e.g., PhD, DVM) in Toxicology or a closely related discipline, plus 5+ years, or a Master's Degree plus 15+ years, of relevant pharmaceutical industry experience • Demonstrated expertise in the design, oversight, interpretation, and reporting of nonclinical safety assessment studies supporting drug development • Proven experience serving as the nonclinical safety representative on cross-functional drug development teams and contributing to regulatory submissions (e.g., INDs, CTAs, BLAs/MAAs) • Strong knowledge of global regulatory requirements and nonclinical safety strategies across all stages of pharmaceutical development Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to