Jobs / United States / Astrazeneca Pharmaceuticals Lp
Associate Director, Oncology Targeted Discovery
Astrazeneca Pharmaceuticals Lp · 🇺🇸 US - Cambridge Kendall SQ - MA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Astrazeneca Pharmaceuticals Lp paid sponsored hires in similar roles15 certified filings for “Associate Director Oncology Outcomes Research” (Medical Scientists, Except Epidemiologists) in MD: $126k–$185k, median $140k. Most were filed at wage level II (47%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
The US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Astrazeneca Pharmaceuticals Lp →
About the role
Summary: We are seeking a highly motivated Associate Director with strong scientific, managerial, and strategic experience in oncology research to join our team in Kendall Square, Cambridge, MA. As an Associate Director in Oncology Targeted Discovery within the Oncology R&D Department, you will be a key leader of a team focused on supporting oncology projects through the drug discovery process. You will bring your theoretical and practical expertise in cancer biology to discover medicines that will have direct impact on the future of targeted cancer therapeutics. If you want a chance to have a direct impact on the next generation of cancer therapies, this is the role for you. You will lead a team of laboratory-based scientists within the Oncology Research group who design, conduct and analyze in vitro experiments to evaluate candidate drug targets and assess the function of candidate oncology drugs. This will include identifying and onboarding the relevant disease models, identifying biomarkers of target engagement, and evaluating the pharmacologic effects of experimental compounds in cancer cells and/or cell-free assays. You may also review emerging literature and internal data to identify new targets and contribute to target nomination, evaluation, and validation activities. Required Qualifications: • PhD with 6+ years of industry research experience in Biology, Oncology, Cell/Molecular Biology, Biochemistry, Pharmacology or related scientific area • OR Masters degree and 10+ years of industry research experience in Biology, Oncology, Cell/Molecular Biology, Biochemistry, Pharmacology or related scientific area • Experience in industry or academia developing, executing, and/or overseeing in vitro studies for the analysis of human tumor cell biology (e.g. cell culture, cell signaling bioassays, high-content imaging, cell death measurement, live-cell reporters, and mRNA/protein expression assays in primary or cell line cultures). Demonstrated track record of delivering data towards mechanism of action studies for cancer therapeutics, and planning and executing assay cascades to support early drug development. • Strong background and experience in cancer biology, cell biology, genetics, cell signaling, and molecular biology • Depth of understanding of solid tumor and hematology cancer models and clinical landscape • In depth knowledge of molecular biology, including assessment of intracellular signaling, generation of cell-based reporter assays, experience with genetic perturbation technologies (siRNA/shRNA/overexpression), and generation and analysis of transcriptomic, proteomic, and genomic data • Experience successfully analyzing and interpreting large datasets and generating testable hypotheses from these analyses • Demonstrated self-starter with ability to work well independently and to collaborate with teams with diverse background and expertise, to execute assigned tasks in a manner consistent with project goals • Track record of successful team management skills, preferably with multiple years’ experience managing multiple direct reports • Interpersonal and communication skills required to identify key scientific questions arising from diverse scientific areas, and present effectively to broad audiences, both within and outside of your immediate team. Ability to report and communicate data to leadership in a clear and concise manner, with a comprehensive understanding of its implications within the overall context of drug discovery. • Demonstrated experience incorporating AI tools into your scientific reasoning and workflows, validating ideas generated by AI, and building and implementing AI agents to accelerate drug discovery efforts • Creative problem-solving skills, with independent initiative to address