Jobs / United States / Astrazeneca Pharmaceuticals Lp
Director, Immunology Scientific Innovation
Astrazeneca Pharmaceuticals Lp · 🇺🇸 US - Cambridge Kendall SQ - MA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Astrazeneca Pharmaceuticals Lp paid sponsored hires in similar roles4 certified filings for “Associate Director, Precision Medicine” (Medical Scientists, Except Epidemiologists) in MA: $179k–$260k, median $215k. Most were filed at wage level II (75%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
The US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Astrazeneca Pharmaceuticals Lp →
About the role
Location: Cambridge, Massachusetts Working model: Hybrid; minimum of three days per week onsite Relocation: Relocation may be considered for qualified candidates currently located outside the Boston area. Position Summary AstraZeneca is advancing the science of immunology with the ambition of moving beyond symptom control toward disease modification, durable remission and, ultimately, the potential for curative approaches. As part of this ambition, AstraZeneca is exploring cell therapy strategies designed to reset the immune system by addressing the underlying drivers of immune-mediated disease, including ex vivo and in vivo CAR-T approaches. We are seeking an accomplished scientific leader to join us as Director, Immunology Scientific Innovation in the cell therapy discover team. The successful candidate will bring deep expertise in immunological disease biology and apply this knowledge to shape differentiated therapeutic strategies and discovery programs. The role will complement AstraZeneca’s cell therapy capabilities by connecting disease biology, drug discovery and innovative cell therapy approaches. The Director will lead laboratory-based scientists in Cambridge, MA and work collaboratively across disciplines and functions to translate biological insights into the next generation of medicines for immune-mediated diseases. This position requires a Boston-area presence to support the leadership of laboratory-based teams and scientific collaboration. Key Responsibilities • Provide scientific leadership: Define and advance scientific strategies in immunological disease biology, including disease mechanisms, biological pathways and immune-cell biology, to inform therapeutic hypotheses and discovery priorities. • Shape discovery strategies: Develop and implement discovery strategies for immune-mediated diseases, with particular relevance to inflammatory bowel disease and other B-cell- and T-cell-mediated diseases. • Translate biology into therapeutic opportunities: Apply a deep understanding of disease biology to identify, evaluate and prioritize mechanisms and therapeutic opportunities capable of addressing the underlying drivers of disease. • Advance drug discovery and development programs: Contribute to and lead programs from early discovery toward clinical development, applying sound scientific judgment and drug-development experience to critical program decisions. • Lead and develop scientific talent: Recruit, lead, mentor and develop a high-performing scientific team, fostering scientific rigor, curiosity, collaboration, accountability and continuous learning. • Build external partnerships: Establish and maintain productive relationships with AstraZeneca colleagues, external scientific experts, academic institutions and other collaborators. • Ensure compliance and quality: Ensure that research activities are conducted in accordance with applicable scientific, regulatory, ethical and AstraZeneca standards. Essential Qualifications Scientific Expertise • Advanced degree: PhD or equivalent advanced degree in immunology, molecular biology, cell biology or a related scientific discipline. • Immunological disease biology: At least 5 years R&D experience in studying the mechanisms and biological drivers of immune-mediated diseases. • Immune-cell biology: At least 3 years expeience in studying B-cell and/or T-cell biology and their roles in immune-mediated disease. • Inflammatory bowel disease: At least 5 years experience in inflammatory bowel disease and/or intestinal immunology is highly desirable. Drug Discovery and Development • Industry experience: At least 5 years experience in the pharmaceutical or biotechnology industry. • Translational expertise: Demonstrated ability to translate biological insights into dr