Jobs / United States / Abbvie INC
Senior Scientist II, Analytical Development
Abbvie INC · 🇺🇸 San Diego, CA, US
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 177 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 94 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Abbvie INC paid sponsored hires in similar roles2 certified filings for “Scientist I, Formulation and Process Development” (Chemists) in CA: $135k–$142k, median $139k. Most were filed at wage level III (50%) — 3 lottery entries, ≈46% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Abbvie INC
The US Department of Labor certified 177 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 94 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Abbvie INC →
About the role
We are seeking a Senior Scientist II to join our experienced, fast-paced, and collaborative Analytical Development team. The successful candidate will provide scientific and technical leadership for analytical characterization of mRNA-based therapeutics and targeted lipid nanoparticle formulations. This role will focus on developing and implementing robust analytical methods for pipeline support, with particular emphasis on RNA and lipids characterization, routine assay development, workflow optimization, and laboratory automation. The scientist will work closely with discovery, formulation, process development, and other cross-functional partners to advance product and process understanding, support candidate selection, and expand the analytical capabilities of the mRNA and lipid nanoparticle platform. Key Responsibilities • Lead analytical method development and characterization activities for mRNA drug substance and mRNA-based lipid nanoparticle programs, with emphasis on pipeline support and candidate selection. • Develop, implement, and troubleshoot fit-for-purpose methods for routine and non-routine analysis of RNA, lipids, lipid-related impurities, oligonucleotides, and proteins using techniques such as liquid chromatography with various detection modes (e.g. UV, CAD, MS, MALLS, Fl), capillary electrophoresis, and plate-based assays. • Design analytical strategies that support product characterization, process understanding, comparability, stability, and method qualification or transfer activities, as needed. • Establish efficient, reproducible workflows for analytical testing, data processing, and interpretation, and identify opportunities to streamline or automate routine activities. • Investigate complex analytical problems, evaluate emerging technologies, and introduce new capabilities that address program and platform needs. • Partner with formulation, discovery, process development, and other cross-functional teams to characterize lipid nanoparticle composition, product quality attributes, and related impurities. • Contribute to characterization of plasmids and assessment of relationships between plasmid attributes and mRNA product quality, as appropriate. • Represent Analytical Development on pipeline, technology development, and platform teams, and communicate results, risks, and recommendations clearly to stakeholders. • Provide scientific guidance and technical mentorship to junior scientists and contribute to analytical best practices within the sub-team. • Author and review technical reports, analytical procedures, study protocols, and other scientific documentation. Qualifications Required • Bachelor’s Degree or equivalent education and typically 12 years of experience, Master’s Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience. • Experience developing analytical methods for RNA, oligonucleotides, lipids, biologics, or other complex therapeutic modalities. • Strong understanding of analytical method development, troubleshooting, data interpretation, and fit-for-purpose method design. • Demonstrated ability to independently define scientific approaches, solve complex technical problems, and lead analytical activities. • Strong technical writing and documentation skills. • Strong written and verbal communication skills and demonstrated ability to work effectively in multidisciplinary teams. Preferred • Experience characterizing mRNA drug substance, lipid nanoparticles, plasmids, or lipid-related impurities. • Experience with capillary electrophoresis, MALS, mass photometry, plate-based assays, or complementary biophysical techniques. • Experience implementing automated or high-throughput analytical workflows. • Experience with analyt