Jobs / United States / Abbvie INC
Senior Scientist, siRNA Therapeutics & Delivery
Abbvie INC · 🇺🇸 Cambridge, MA, US
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 177 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 94 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Abbvie INC paid sponsored hires in similar roles1 certified filing for “Senior Scientist II, Biologics Analytical R&D” (Biochemists and Biophysicists) in MA: $155k–$155k, median $155k. Most were filed at wage level III (100%) — 3 lottery entries, ≈46% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Abbvie INC
The US Department of Labor certified 177 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 94 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Abbvie INC →
About the role
At AbbVie, we are dedicated to solving some of the world’s most complex and serious diseases. Our mission is to develop and deliver advanced therapeutics that change lives. We are looking for talented, passionate, and driven individuals to join our Biotherapeutics and Genetic Medicine (BGM) team. As a Senior Scientist in our siRNA group, you will be part of an innovative team focused on advancing RNA-based therapies that have the potential to revolutionize patient care. AbbVie is looking for a Senior Scientist I/II to join our siRNA group within the Biotherapeutics and Genetic Medicine (BGM) department. This role will involve designing and executing innovative experimental approaches to address key scientific challenges related to oligonucleotide therapeutics and to enable siRNA delivery for extrahepatic pipeline development. The successful candidate will drive scientific innovation, identify new methods and techniques, and collaborate across functions to support the development of novel RNA-based therapies. Responsibilities: • Lead research efforts within a cross-functional team to advance siRNA therapeutics development for ex-hepatic pipelines • Design, evaluate, and develop novel ex-hepatic siRNA delivery platforms for targeted delivery to tissues of interest • Conceive and execute proof-of-concept experiments to validate scientific hypotheses and address technical challenges with high-quality results. • Develop in vitro, ex vivo, and in vivo assays to assess siRNA candidates and delivery technologies in support of program objectives. • Work independently and maintain a high level of productivity in the laboratory, ensuring efficiency and scientific rigor. • Analyze and interpret multidisciplinary data to generate actionable conclusions and guide future experimental directions. • Acquire deep knowledge of RNA biology and siRNA therapeutics to support programs across multiple stages of development. • Collaborate and effectively communicate results with key stakeholders and cross-functional teams throughout the organization. • Contribute as a primary author to scientific publications, presentations, and/or as a primary inventor of patent applications. • Mentor and support junior scientists within the team. • BS, MS, or PhD in molecular biology, RNA biology, cell biology, pharmaceutical sciences, biomedical engineering, or or a related scientific discipline, with typically 0-4+ (PhD), 8-10+ (MS), or 10-12+ (BS) years of relevant experience. • Hands-on experience in designing and executing in vitro and in vivo studies to evaluate siRNA delivery platforms, including assessments of cellular uptake, target knockdown, delivery efficiency and biodistribution. • Demonstrated expertise in siRNA therapeutics, including the design, development, characterization and optimization of siRNA sequences and delivery systems. • Proven experience with siRNA and antibody-oligo-conjugates (AOCs) is highly desirable. • Extensive hands-on experience and techniques for molecular and RNA biology, including cell culture, RNA extraction, RNA quantification (RT-PCR, qPCR, ddPCR), next-generation sequencing (NGS), protein quantification (ELISA, Western Blot, JESS), flow cytometry and other biomarker quantification. • Proven ability to develop, troubleshoot and refine assays to enhance sensitivity, reproducibility, and throughput. • Highly self-motivated and capable of thriving in a fast-paced, collaborative team environment. • Strong written and verbal communication skills, with experience contributing to technical reports, publications, or regulatory documentation. Why AbbVie? AbbVie is a global biopharmaceutical company committed to bringing innovative medicines to patients in need. We offer a collaborative w