Jobs / United States / Astrazeneca Pharmaceuticals Lp
Director, Discovery Project Management, Cell Therapy Autoimmune
Astrazeneca Pharmaceuticals Lp · 🇺🇸 US - Cambridge Kendall SQ - MA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Astrazeneca Pharmaceuticals Lp paid sponsored hires in similar roles1 certified filing for “Associate Director, Oncology Portfolio Analytics” (Management Analysts) in MD: $157k–$157k, median $157k. Most were filed at wage level II (100%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
The US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Astrazeneca Pharmaceuticals Lp →
About the role
Introduction to Role Are you ready to co-own the execution of next-generation cell therapy programs and help transform groundbreaking science into meaningful outcomes for patients? As Director, Discovery Project Management, Cell Therapy Autoimmune, you will play a critical role in driving discovery-stage programs focused on autoimmune and immune-mediated diseases. Working in partnership with Bioscience Leads, you will provide strategic project leadership across a portfolio that spans from pre-Target Selection Investment Decision through preclinical proof of concept and transition into Global Product Teams. Our portfolio includes LVV-based CAR-T, LNP, autologous, and allogeneic cell therapy approaches. This role operates within a unique partnership model where scientific leadership and project leadership work hand-in-hand to ensure clear decision-making, effective execution, and timely delivery of program objectives. Within a highly collaborative and agile environment, you will help shape how discovery projects are managed while contributing directly to programs advancing toward the clinic. Accountabilities Project Leadership & Execution • Partner closely with Bioscience Leads to drive execution, delivery, and decision-making across discovery-stage programs. • Co-own program scope, timelines, budgets, risks, and milestones. • Facilitate cross-functional collaboration and alignment to ensure successful project delivery. • Challenge assumptions, drive accountability, and proactively address barriers to progress. Project Planning & Coordination • Lead project initiation activities including project charters, RACI development, governance structures, and team operating models. • Develop and maintain integrated project plans and schedules. • Identify project risks and opportunities early and coordinate appropriate mitigation activities. Governance & Decision Support • Lead and facilitate project team meetings and product development reviews. • Manage project interdependencies, scope adjustments, and escalation pathways. • Maintain project plans and governance documentation, ensuring alignment with organizational processes. • Prepare project updates, dashboards, and milestone reporting for leadership teams. AI-Enabled Project Management • Leverage AI-enabled solutions to enhance project scheduling, risk analysis, reporting, and decision support. • Promote responsible and effective use of AI tools across project teams. • Stay current with emerging technologies that improve project execution and operational efficiency. Stakeholder Management • Partner effectively with scientific, technical, and business stakeholders. • Support governance reviews and investment decision activities. • Drive clear communication and alignment across global cross-functional teams. Program Transfer & Closeout • Lead the successful transition of programs to Global Product Teams and incoming Global Project Managers. • Ensure readiness of deliverables, data packages, and handover documentation. • Capture and apply lessons learned to continuously improve project execution practices. • Coordinate project handovers with regional teams, including partnerships supporting China Discovery and investigator-initiated trial preparations. Essential Requirements • Bachelor's degree with a minimum of 10 year's experience. • Significant project management experience within pharmaceutical, biotechnology, drug discovery, or early development environments. • Strong understanding of autoimmune and immune-mediated disease biology and drug development. • Demonstrated success managing complex, cross-functional projects through key development milestones and investment decisions. • Experience partnering directly with scientific leaders to drive project