Scientist I, Dermatology/Immunology

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About the role

AbbVie’s Immunology R&D organization is looking for a highly motivated Scientist I to join our Dermatology Discovery team at the Cambridge Research Center in Cambridge, MA. This researcher will contribute to the identification and validation of novel therapeutics for inflammatory skin diseases. The Dermatology Discovery team applies human disease transcriptomic and multi-omics data sets in combination with wet-bench science to perform mechanistic in vitro studies with the overarching goal to elucidate disease-driving mechanisms that will advance innovative therapeutic strategies. The successful candidate will play a key role in the preclinical research team by conducting in vitro models focusing on human translation to HS and PsO.   The ideal candidate is scientifically curious, collaborative, enthusiastic, skilled, and dedicated. This position requires passion, attention to detail, prior hands-on experience, and teamwork within a fast-paced drug discovery environment.  Key Responsibilities:  • Sterile cell culture (cell lines and primary human and murine cells)  • Process and analyze ex-vivo human tissues for disease-relevant endpoints   • Perform analyses using the following techniques:  •      Flow cytometry  •      Quantitative PCR  •      Protein analyses – ELISA, MSD and multiplex assays  •      Western blotting  •      Microscopy  • Develop and implement assays that monitor cellular processes  • Analyze data using appropriate statistical methods and communicate findings through presentations and scientific discussions  • Maintain detailed experimental records and ensure compliance with electronic laboratory notebook • Prior hands-on experience with keratinocytes, fibroblasts, and immune cells (Th17 T cell differentiation, macrophage polarization) is a plus • Candidates with prior experience in complex human in vitro model will receive extra consideration • Bachelor’s degree in molecular biology, immunology or other biological sciences (BS/BA) with 5 years of experience • Master’s degree with 2 years of experience is desired Key AbbVie Competencies: • Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance • Learns fast, grasps the “essence” and can change course quickly • Raises the bar and is never satisfied with the status quo • Creates a learning environment, open to suggestions and experimentation for improvement • Embraces the ideas of others and nurtures innovation to make possibilities real Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​ • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​ • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​ • This job is eligible to  participate in our short-term incentive programs.  ​ Note: No amount of pay is  considered to be wages or compensation until such amount is earned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolute discretion,  cons

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