Senior Manager, Finance – Business Partnering & GTN , OBU Canada

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About the role

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, ambitious thinking and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe. Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head office and BlueSky Hub in downtown Toronto are purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects. Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention. As a Senior Manager, Finance, you will Lead financial oversight and business partnering for assigned Oncology therapeutic areas, with full accountability for the P&L. You will guide planning, budgeting, month-end reporting, resource allocation, and strategic decisions.You will also lead end-to-end gross-to-net (GtN) financial stewardship for Oncology, including planning, accrual governance, controls, and performance reporting across brands and channels. You will translate payer, pricing, discount, distribution, patient support program, and evidence dynamics into clear financial insights that support near- and long-term decisions. Key Accountabilities • Own the P&L: Own the end‑to‑end P&L for the assigned Therapeutic Area (TA), ensuring accuracy of revenue and expense recognition, gross‑to‑net, OPEX, and profitability outcomes; drive actions to deliver targets. • Partner with the business: Translate brand and functional strategies into financial implications, options, and recommendations for senior leaders. • Lead planning and reporting: Manage annual budgets, in-year updates, month-end close, forecasts, and variance commentary for therapeutic area P&Ls and Oncology GtN. • Month‑End Close & Performance Reporting : Run month‑end activities for the TA & OBU GTN; deliver accurate reporting and clear variance commentary linked to business drivers across the full P&L. • Cost Excellence & Resource Allocation : Challenge spending plans, identify efficiencies, and support reallocation to high‑impact initiatives while maintaining compliance and controls. • Commercial Analytics : Assess price/volume/mix, gross‑to‑net impacts, investment returns, and brand/competitor dynamics to inform decision‑making and portfolio choices. • Strengthen GtN stewardship: Lead accrual governance, controls, documentation, SOX alignment, and audit readiness across brands and channels. • Improve investment decisions: Challenge spending, identify efficiencies, and redirect resources to high-impact priorities. • Provide commercial insight: Analyze price, volume, mix, GtN impacts, returns on investment, and market dynamics to inform portfolio choices. • Manage risks and opportunities: Quantify financial impacts across the P&L and GtN, including rebate, patient support program utilization, and returns trends; establish clear actions, owners, and timelines. • Evaluate business cases: Build, assess benefits, costs, trade-offs, P&L impact, and post-implementation performance. • Build capability and simplify: Strengthen financial understanding, decision forums, data quality, reporting, and processes in partnership with the Finance Director. Essential Qualifications • Bachelor’s degree in A

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