Jobs / United States / Natera INC
Senior Manager of Software Engineering & DevOps (DSPE)
Natera INC · 🇺🇸 San Carlos, CA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 12 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Natera INC paid sponsored hires in similar roles1 certified filing for “Manager, Software Engineering” (Computer and Information Systems Managers) in NY: $201k–$201k, median $201k. Most were filed at wage level II (100%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Natera INC
The US Department of Labor certified 48 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 12 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Natera INC →
About the role
This is an exciting opportunity to lead a Software Engineering & DevOps team at Natera, a global leader in precision medicine and genomics testing. As a Senior Manager of the Software Engineering & DevOps team inside our Data Science Production Engineering (DSPE) department, you will have the opportunity to build with Natera's diverse and ultra-large data sets (up to PB size), create software and automation solutions for the most cutting-edge medical diagnostics and genomics applications, and make real impact by delivering reliable, efficient, high performance software products and data/cloud/automation systems to support Natera's Lab Operations and Genetic Counselor/Lab Director teams, and ultimately impact patients' medical outcomes. PRIMARY RESPONSIBILITIES: Leadership • Lead a DevOps team, working closely with other DSPE teams, to develop, test, deploy, maintain, and update DSPE's data platforms, cloud platforms, automation systems, and analytics systems • Manage the DevOps team, to achieve the timely and efficient delivery of software products and systems with correct and robust functionality. • Train and coach team members on new technologies, procedures, and guidelines/best practices. • Create and maintain operational visibility (e.g., workload, productivity, etc.) of the DSPE DevOps team. Technical • Translate DSPE's business needs and project requirements into technical specifications and implementation plans. • Working with DSPE leadership teams, create suitable system architecture and infrastructure design documents that can be efficiently implemented and maintained. • Maintain and optimize infrastructure performance, monitoring key system metrics including network I/O, disk I/O, memory allocation, and compute resource utilization. • Contribute to key development, testing, deployment, validation, maintenance, and update activities. Quality, Compliance, and Documentation • Improve and enforce procedures for work efficiency, quality, and compliance. • Lead and manage the technical documentation's creation and maintenance/update for all DSPE DevOps owned software tools and systems, for example, design specifications, software verification and validation (V&V) protocols and reports, deployment/update/maintenance records, user guides, etc. • Create training materials, and contribute to training activities, on DSPE DevOps owned software tools and systems. Cross-Functional • Engage proactively and directly with engineering and operational stakeholders to align infrastructure roadmaps, resolve technical dependencies, and report platform performance metrics. • Represent the DSPE DevOps team in stakeholder meetings. QUALIFICATIONS: • Minimal Bachelor's Degree in Computer Science, Software Engineering, Bioinformatics, or a related field. Advanced degrees preferred. • Minimal 10 years of relevant industry experience for candidates with only a Bachelor's Degree. Minimal 8 years of relevant industry experience for candidates with a Master's Degree. Minimal 4 years of relevant industry experience for candidates with a Doctorate degree. • Minimal 3 years of working experience in a highly regulated environment, e.g., CLIA and/or FDA compliant settings. • Minimal 3 years of management experience leading a DevOps team, or a software development team. • Demonstrable experience in designing, delivering, and maintaining/updating custom-developed software tools or systems for production environments, preferable in high-throughput settings (e.g., heavy traffic and/or high computation load). • Demonstrable experience in creating software design specification documents, verification and validation documents, and user manuals. KNOWLEDGE, SKILLS, AND ABILITIES: • Excellent Python programming skills, with substantial clou