Jobs / United States / Twist Bioscience Corporation
Sr Director, Commercial Operations
Twist Bioscience Corporation · 🇺🇸 USA - South San Francisco, CA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 11 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest May 2026) — the step every H-1B hire needs first. USCIS also records 9 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Twist Bioscience Corporation
The US Department of Labor certified 11 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest May 2026) — the step every H-1B hire needs first. USCIS also records 9 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Twist Bioscience Corporation →
About the role
Twist Bioscience is looking for a Director, Commercial Operations to lead, scale, and optimize key operating disciplines across our global commercial organization. In this role, you will lead cross-functional process improvements, oversee sales and project management operations, establish commercial reporting standards, and partner with executive leadership to drive scalable growth and an insights-driven sales approach. What You’ll Be Doing • Manage Commercial Operations team consisting of Customer Master Data Specialist, Process Improvement, Sales Operation, Business Management, and Project Management Teams. • Lead cross-functional process improvements projects (pricing strategy, discount governance, contracting) and implement new process (i.e., multi-currency and Distributor Flow enhancement). • Create a center of excellence for Commercial Reporting. • Develop and implement strategic plans to improve performance in all aspects of Commercial Operations. • Partner with Sales and Marketing to evaluate new technology that could improve sales and marketing operations. • Structure, develop, and implement scalable process and procedures to implement an insights-driven commercial approach and top-tier Customer engagement. • Participate in hiring, training, and ongoing coaching of leadership staff to ensure execution of sales performance. • Conducts sales performance reviews on a regular schedule. • Partners with HR in all employee relation activities including Process Improvement plans, coaching, steps of discipline and termination. • Determining staffing needs based on workload requirements and recruiting and hiring staff accordingly. • Available as resource and mentor to leadership and team members. • Assess whether current sales strategies are sufficient for meeting company sales goals. • Support lead governance and handoff process from Digital Marketing, ISS, and Field Sales to ensure smooth handoff and reporting capability. • Collaborate cross-organizationally to create a robust performance and opportunity metrics that the Executive Team will use to make informed decisions surrounding commercial and go-to-market strategy. What You’ll Bring to the Team • Degree in Biology, Biochemistry, or a related field • 10+ years of progressive commercial and technical experience in the life sciences/biotech space • 5+ years in managerial and supervisory roles leading cross-functional teams. • Demonstrated expertise in sales planning, forecasting, pipeline management, CRM systems (Salesforce), commercial analytics, and process improvement within a fast-paced B2B environment. Twist Bioscience is a leading synthetic biology and genomics company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Twist uses this platform to serve customers working in healthcare, agriculture, industrial chemicals, academic research and beyond, with products spanning synthetic genes and oligos, NGS target enrichment, and antibody discovery and development services. The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations. San Francisco Bay Area Pay Range $224,000 — $289,000 USD