Scientist I, Disease Biology

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About the role

Our Mission Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission . Diversity at Altos Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment. What You Will Contribute To Altos We are looking for a talented and versatile Scientist I to join Discovery Science at Altos Labs. Our team uses functional genomics to unravel the deep biology of cellular rejuvenation and to restore cell health and resilience. In this role you will develop physiologically relevant in vitro and ex vivo disease models and integrate these with in vivo studies to identify interventions that reverse disease-associated cell states. If you have a strong foundation in molecular, cell, and disease biology, hands-on experience with in vitro and in vivo disease assays, and a passion for reversing disease states, we’d love to have you on the team. Responsibilities • Design and execute innovative research strategies to identify causal regulators of cell state, aging, regeneration, and disease biology. • Develop, benchmark, and validate disease cell models of age-related and disease-associated cell states. • Scale assays to screen candidate interventions across cell models, and contribute to data-driven prioritization decisions on which candidates and which models to advance. • Design, conduct, and interpret in vivo studies to evaluate candidate interventions and benchmark disease models against in vitro findings. • Elucidate the mechanisms of action underlying promising interventions to identify and prioritize therapeutic targets and modalities. • Support and manage internal/external collaborations across one or more multidisciplinary projects to accelerate essential research activities. • Develop project-specific experimental strategies, techniques, and procedures. • Collaborate closely with other scientists and cross-functional teams to integrate multidimensional datasets and generate actionable biological insight. • Contribute to the writing and dissemination of research results. Who You Are Minimum Qualifications • PhD in Biology, Cell Biology, Physiology, or a related field, with 0-3 years of post-PhD experience. • Proven track record of elucidating complex age-associated disease mechanisms, including but not limited to kidney, lung, liver and skin indications. • Experience developing and validating cell-based disease assays, including benchmarking assay performance. • Strong hands-on experience conceptualizing and performing rodent in vivo disease assays, with a background in relevant laboratory techniques and methods. • Excellent professional writing skills and the ability to communicate through writing and presentations to a variety of audiences, from senior executives to entry-level employees. • Problem-solving skills sufficient to identify issues, conduct research, and develop innovative solutions. • Ability to maintain cooperative working relationships with a broad range of people, including staff colleagues, lab members, faculty, outside agencies and collaborators, and the community. • Demonstrated high productivity and ability to complete work in a timely manner. • Ability to organize work and set pri

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