Jobs / United States / Tessera Therapeutics INC

Tessera Therapeutics INC

Research Associate II, Cell Therapy Platform

Somerville, Massachusetts, United States Posted today

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One solid signal, not two. Worth applying, and worth asking about sponsorship early.

  • Employer is on a government sponsor recordThe US Department of Labor certified 3 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Apr 2026) — the step every H-1B hire needs first.
  • The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
  • No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area.
  • Confirmed live todayWhen a source last listed this job as open.
Details and sources
Employer is on a government sponsor record
The US Department of Labor certified 3 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Apr 2026) — the step every H-1B hire needs first. Source: LCA disclosure data (US Department of Labor (OFLC)).
No salary bar for this route
H-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.

US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).

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About the role

About the Role Tessera is developing in vivo CAR-T therapies, using targeted lipid nanoparticles to deliver CAR mRNA directly to T cells. We're looking for a Research Associate to join our Platform team. You'll run experiments that move our CAR-T programs forward, generate high-quality data, and build your skills in experimental design and analysis alongside experienced scientists. This role suits someone who is detail-oriented, eager to learn, and excited to grow their scientific career in cell therapy. Your experience includes… • BS in biology, biochemistry, molecular biology, immunology, or related field with 2+ years of industry experience, or an MS with 0–2 years of industry experience (co-ops and internships count toward the degree, not work experience) • Working knowledge of immune-cell biology, with hands-on experience in mammalian or primary cell culture and flow cytometry; exposure to data analysis tools such as FlowJo and to functional assays such as cytotoxicity, proliferation, or cytokine release is a plus • Laboratory experience in an academic or industry setting, with the ability to follow established protocols accurately and keep thorough, organized records • Strong data analysis skills and attention to detail • Clear communication, a collaborative spirit, and a positive, flexible approach to changing priorities Nice to have… • Experience with CAR-T or other engineered cell therapies • Experience with mRNA or lipid nanoparticle delivery and characterization, including dose-response studies • Familiarity with in vivo models for cell therapy, such as humanized mouse models • Experience with plate-based assays, ELISA, or qPCR • Familiarity with basic statistics or data tools You are interested in… • Executing experiments using established methods and techniques, including cell culture and flow cytometry, with supervision and guidance from senior team members • Planning basic to moderately complex experiments for specific projects, consulting with your supervisor on design and methods • Analyzing data, evaluating its quality, and recognizing patterns, anomalies, or inconsistencies, reporting unexpected results to your supervisor • Operating and maintaining laboratory equipment, and documenting experiments and results accurately in the electronic lab notebook • Contributing data, analyses, and summaries to project team reports and meetings • Helping troubleshoot routine technical issues and beginning to suggest improvements or alternative approaches • Managing and prioritizing your work as project needs change • Building working relationships within your team and learning how your work connects to broader program goals About you: You're an early-career scientist who loves time at the bench and wants to build your career in cell therapy. You've worked hands-on with mammalian or primary immune cells and run flow cytometry, and you're comfortable following established protocols closely while keeping careful, organized records. On the Platform team, you'll put those skills to work running the cell culture, flow-based, and functional assays that test how well our targeted LNPs deliver CAR mRNA to T cells. You look closely at your data, notice when something doesn't look right, and raise it with your team. You adapt easily when priorities shift, communicate clearly, and are eager to take on more of the experimental design as your skills grow. Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence. Meet your Manager: All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening. Florence Car

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