Director, Implementation Science

Director, US Policy Evidence Location: Wilmington, DE About AstraZeneca AstraZeneca is a global, innovation-driven BioPharmaceuticals business that focuses on the discovery, development, and commercialization of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca we’re dedicated to being a Great Place to Work, where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development. The Role The Director, US Policy Evidence is a strategic leadership role within the US Medical Affairs, Implementation Science and Policy team. The role is accountable for building and operationalizing a policy evidence ecosystem that strengthens AstraZeneca's position as a practice-defining innovator and thought leader across priority therapeutic areas. The role advances the generation and dissemination of policy-relevant evidence that accelerates access and drives measurable improvements in care quality and patient outcomes. Reporting to the Senior Director, Implementation Science & Policy , and partnering closely with therapeutic area (TA)-aligned implementation science leads, real world evidence directors, and federal and state government affairs teams, the Director develops and executes a policy evidence planning framework aligned to brand and Medical strategy, ensuring cross-functional integration across US Medical, Government Affairs & Policy, Market Access, and Commercial teams. The Director translates data-driven insights into policy-enabling evidence that positions Medical Affairs as a strategic partner in policy advocacy. This role requires deep expertise in health policy, payer strategy, and quality and value-based care ecosystems, combined with strong business acumen and excellent interpersonal skills. The Director maintains current awareness of the evolving US legislative, regulatory, and reimbursement landscape, and applies AI-enabled tools responsibly to support narrative generation, evidence customization, and policy brief development. Key Responsibilities Policy Evidence Strategy • Lead the development, socialization, and operationalization of a policy evidence planning framework aligned to brand and Medical strategy, ensuring consistent application and cross-functional integration across teams. • In partnership with Real World Evidence & Implementation Science Directors, design and generate practice-defining evidence with clear clinical, economic, and policy impact. • Drive broad dissemination of policy-relevant models to priority states with multi-stakeholder audiences including payers, employers, and policymakers, and extend approaches to additional therapeutic areas and international markets where feasible. Government Affairs & Cross-Functional Partnership • Partner with Government Affairs & Policy teams to identify, prioritize, and advance policy initiatives by providing data-enabled insights that strengthen AstraZeneca's policy positions and market-shaping efforts. • Co-lead care delivery policy shaping workstreams and coordinate joint Medical-Government Affairs briefings to align internal stakeholders and inform external engagement. • Collaborate with US Market Access, Commercial Insights, and Brand teams to translate the product value proposition into policy-enabling strategies with tangible, measurable outcomes. Policy Education & Medical Team Capability Building • Develop and deliver policy education content to build capability across medical teams and leadership, covering th