Senior Medical Program Manager (MPM) – One Medical Early Assets

Job title:  Senior Medical Program Manager (MPM) – One Medical Early Assets Location: Cambridge, MA About the Job   The MPM will provide program management expertise, team and portfolio management, and strategic operational support across the One Medical early asset portfolio, enabling integrated medical inclusion from discovery through proof of concept. This individual will work closely with the Medical Program Lead (MPL), Early Asset Global Medical Leads (GMLs), and Global Medical Teams (GMTs), both internally and with alliance partners where applicable, to ensure medical knowledge and insights flow seamlessly across the early-development value chain, forging aligned partnerships across R&D. The position sits within the NextGen Immunology (NGI) team but carries responsibility across One Medical SPC and Gen Meds. Working in a matrix environment, the MPM drives strategic direction and operational execution, ensuring teams are empowered to innovate boldly together across the early medical lifecycle. Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions. About Sanofi We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. Main Responsibilities • Provide program management expertise, team and portfolio management, and strategic operational support across the One Medical early asset portfolio • Enable integrated medical inclusion across early-stage assets from discovery through proof of concept • Drive strategic direction and operational execution, ensuring the GML has line of sight across R&D to deliver impact in the Global Project Teams (GPTs) from M2 • Position Medical to co-lead Disease Area Strategies in partnership with R&D • Forge strategic partnerships and shared governance with the TMU ECET Program, CSU eProtocol, and Patient Driven Medicine Development • Plan, Coordinate and Co-partner on driving the early iEGP (Integrated Evidence Generation Plan) roadmap at both disease area and asset level • Drive evidence generation prioritization in partnership with the GML • Design, coordinate, and co-lead a Global Medical Team (GMT) system that ensures resource efficiency and a strong matrixed network across global medical, local medical, and cross-functional partners early in the medical lifecycle • Establish a framework for operationalizing medical strategy, tactics, and clinical investment planning for early medical and budget needs as assets advance through the lifecycle, for use by asset and disease area teams • Manage portfolio and operational level activities via the harmonized Program Management Tool used across the MPM organization • Ensure workflows and processes are efficient and compliant with internal SOPs and external guidelines   About You Basic requirements: • Bachelor's degree in Life Sciences, Biomedical Sciences, Pharmacy, Health Sciences, or a related scientific discipline required. Advanced scientific degree (MS, PharmD, PhD, MD) preferred; MBA or equivalent business qualification is a plus. • Minimum 5 years of project/program management, portfolio management, or related experience within the biopharmaceutical, biotechnology, healthcare, clinical research, or scientific environment, with experience supporting cross-functional teams and complex initiatives. • Background in the biopharmaceutical or pharmaceutical industry with direct experience in project/pr