About the role
Do you want to make a global impact on patient health? Do you thrive in a fast-paced environment that integrates scientific, clinical, and commercial domains through engineering and AI? Join Pfizer US Commercial AI Acceleration (AIA) team to leverage cutting-edge technology for critical business decisions and enhance customer experiences for colleagues, patients, and physicians. Our team of engineering, data science, and AI professionals is at the forefront of Pfizer’s transformation into a digitally driven organization, using data and AI to change patients’ lives, leading process and engineering innovations to advance AI and data science applications from prototypes and MVPs to full production.
As an AIA Integrations and DevOps Forward Deployed Engineer (Sr. Manager) on the AIA Full Stack Engineering team, you will be the owner of US Commercial’s AWS accounts and the technical lead for everything infrastructure-related across US Commercial. You will architect, govern, and operate the AWS foundations that AIA’s AI applications and agents run on—including externally hosted, public-facing solutions for sales and marketing—build the integrations that connect them to Pfizer’s enterprise systems, data, and commercial SaaS platforms, and own the CI/CD and DevOps practices that let the team ship secure, reliable solutions from prototype to production at speed.
ROLE RESPONSIBILITIES
1) AWS Cloud Architecture & Infrastructure Engineering
• Own the US Commercial AWS accounts end to end: account structure and vending (AWS Organizations, Control Tower, landing zones, SCPs), governance, guardrails, and lifecycle management, acting as the accountable technical owner with AWS and Pfizer cloud platform teams.
• Act as the technical lead and authority for all infrastructure decisions in US Commercial: define standards, review architectures, and approve designs for AIA and partner teams.
• Own infrastructure-as-code (Terraform, AWS CDK, CloudFormation) and Git-based workflows so every environment is repeatable, auditable, and reviewable.
• Design and operate core AWS services including:
• Compute and runtime: ECS/Fargate, EKS, Lambda, and serverless patterns
• Data and storage: S3, RDS/Aurora, DynamoDB, OpenSearch, and vector stores
• Networking: VPC design, subnets, VPC peering, Transit Gateway, PrivateLink, API and NAT/Internet gateways, Direct Connect/VPN, Route 53, and load balancers
• Architect and operate external hosting for public-facing solutions (CloudFront, WAF, Shield, ACM, edge security, DNS) in line with Pfizer external-hosting and security standards.
• Serve as the expert for AWS AI services: Amazon Bedrock (models, Knowledge Bases, Guardrails, Agents, AgentCore), SageMaker, Amazon Q, and supporting services for RAG (Retrieval-Augmented Generation), agent runtimes, and model access/quota management across accounts.
• Drive cloud cost optimization through right-sizing, tagging, budgets, and FinOps reporting, and own the AWS spend for US Commercial accounts.
2) Integrations & Connectivity Enablement
• Design and build integrations between AIA solutions and Pfizer enterprise systems and commercial SaaS platforms (Adobe Experience Platform, Salesforce/Veeva CRM, data platforms such as Snowflake and Databricks, SharePoint/Microsoft 365, ServiceNow) using APIs, event-driven patterns, and MCP (Model Context Protocol) connectors.
• Own API gateway, service mesh, and messaging patterns (API Gateway, EventBridge, SQS/SNS, Step Functions) that let applications, agents, and data services communicate securely.
• Resolve networking and connectivity blockers for the team: firewall and proxy rules, private endpoints, DNS, certificates, and cross-account/cross-region access.
• Partner with enterprise platform, network, and identity t
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