Senior Principal - Tech Finance Manager

Business Introduction GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver £40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines. Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges. Job Purpose  Accountable for the financial management of [domain/platform team], applying the standards set by central Technology Business Operations. The role owns the budget, forecast, actuals and cost transparency, runs the day-to-day financial operations, and provides accurate, consistent financial inputs into the central DPTF reporting cycles. It gives leadership a clear view of spend, forecast and financial risk, and operates under a dotted line to the Director, Business Operations for financial governance and standards. ROLE SCALE, COMPLEXITY AND IMPACT This is a senior technology finance leadership role with end-to-end accountability for the financial position of the assigned technology domain or platform portfolio. The role integrates complex run, change, supplier, workforce, tooling, licence and investment cost drivers into a single decision-quality view for senior leadership. The post holder manages and assures a complex annual cost base of approximately GBP 25 million, subject to confirmation through the Rewards and Finance calibration process. The role is accountable for forecast integrity, cost control, financial risk, investment insight and the quality of submissions feeding consolidated DPTF reporting and leadership decisions. MARKET AND GEOGRAPHIC SCOPE Global scope across the regions, countries and markets supported by the relevant technology services. The role consolidates financial inputs across geographically distributed teams and suppliers, while addressing differences in currency, local cost structures, market commitments, contractual arrangements and regulatory or control requirements. Experience is required to operate as an independent financial authority for a material global portfolio, withstand senior challenge, identify second-order financial consequences and influence decisions where cost, service resilience, technology risk and strategic priorities compete. Key Responsibilities Budgeting, Forecasting and Performance Own the budget, forecast and actuals, planning and tracking the cost base to the enterprise finance timetable. Analyse variance, risk and opportunity against plan and provide clear commentary and recommendations to leadership. Support business cases, funding requests and investment tracking, with spend decisions owned by the [domain/platform team].   Financial Operations Run financial operations, including accruals, reclasses, cross-charges, purchase orders, invoices and payment follow-up. Support month-end, quarter-end and year-end close for the enterprise finance timetable. Ensure financial transactions and records are accurate, complete and processed within control requirements.   Cost Transparency and Reporting Provide cost transparency, including vendor, contractor and unit-cost views at the level leadership needs. Maintain a financial view of headcount, covering budgeted positions and vacancies. Provide accurate, standardised financial inputs into the central DPTF reporting cycles run by Technology Business Operations.   Contract and Vendor Fi