Senior Accountant

About Us … Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian’s programs apply our cytoDRiVE® technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian’s lead program is currently in clinical development for the treatment of patients with metastatic melanoma and non-small cell lung cancer. We’re proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options. Our Opportunity... We are looking for a highly motivated Senior Accountant with a strong background in general accounting. As a key contributor within the Finance team, you'll own several key areas of the monthly close process and support the company’s financial operations with accuracy, efficiency, and strong attention to detail, helping to drive the development of our first clinical stage autologous cell therapy program targeting solid tumors. You’ll lead and execute core accounting activities including cash reconciliations, accruals, accounts payable, payroll accounting, and other month-end close responsibilities, ensuring timely and accurate financial reporting in a fast-paced and growing biotechnology company environment. As a member of our Finance team, you will be a vital part of a highly collaborative group working to unlock the promise of precision cell therapy for patients, starting with our lead program amsoki -cel (OBX-115), a novel engineered tumor-infiltrating lymphocyte (TIL) cell therapy that uses our proprietary cytoDRiVE ® platform. This is a unique opportunity to be a valuable contributor in a well-funded clinical company with field-leading advisors, best-in-class partners, and an experienced team. This is a Hybrid role based out of our Cambridge, MA location until Q2, 2027 when our Bedford, MA office space expands to become our single MA location You Will... Core responsibilities • Execute month-end, quarter- end and year-end close processes • Prepare journal entries and reconciliations for assigned areas of ownership • Train and provide cross functional support related to the company’s procure - to - pay policies and procedures • Responsible for invoice entry and weekly payment runs • Manage Travel & Expense reporting system (Concur), process (including policy adherence), and journal entries • Execute payroll processing, reporting & accounting • Register & Manage State Withholding Accounts & State Tax Compliance • Manage day-to-day cash and treasury operations, including monitoring bank balances, cash positioning, transfers and bank reconciliations. • Prepare and maintain short-term cash forecasts, partnering with Finance to ensure adequate liquidity for payroll, operating expenses, clinical activities, and other anticipated cash needs. • Ensure compliance with applicable accounting standards, regulatory requirements, and internal controls • Assist with external audits, including preparations of audit schedules and documentation • Identify and implement process improvements to enhance efficiency and accuracy in financial operation You Bring... Core Qualifications • Bachelor’s degree in accounting, Finance or related field . • 5 -7 + years of progressive accounting experience, preferably in the biotechnology, pharmaceutical, or life sciences industry . • Stron