Statistical Science Director

Job Title: Statistical Science Director • Career Level – F • Location: Manyata Tech Park, Bangalore • Therapy area: Oncology • Work Type: Hybrid About AstraZeneca: AstraZeneca is a global, science-led, patient-focused pharmaceutical company that focuses on the research, development, and commercialisation of prescription medicines. We aim to transform the lives of patients with improved outcomes and a better quality of life. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we're dedicated to being a Great Place to Work. Introduction to role: It is an exciting time to join AstraZeneca Oncology. Are you ready to lead statistical strategy that accelerates life-changing medicines to patients? Could you shape how science and data come together to inform bold decisions across global programs? This is your opportunity to drive statistical excellence where it has immediate and tangible impact on development turning points and patient outcomes. As a Statistical Director, you will be responsible for the supervision and development of Bangalore based associates, provide strategic statistical leadership on complex, high-visibility programs, uniting cross-functional teams to deliver robust evidence that stands up to scientific and regulatory scrutiny. You will harness modern methodologies and models to reveal clear signals from complex data, guiding decisive action throughout the drug development lifecycle. Here, your expertise not only sets scientific direction but also improves the pace, quality, and integrity of decisions that matter. Accountabilities: • Statistical Leadership: Set statistical vision and strategy across one or more assests, ensuring coherent design, analysis, and evidence generation plans that de-risk development and improve product value. • Manage a group of staff ensuring delivery of statistical contributions or as a Bangalore region expert support assessments and research within a specialist area of Biostatistics. • Development Strategy and Decision-Making: Quantify benefit, risk, value, and uncertainty for emerging product profiles, informing go/no-go decisions and shaping registration strategies across phases. • Portfolio Delivery: Oversee large, complex projects from early development through commercialization, ensuring on-time, high-quality statistical deliverables that align with regulatory and business objectives. • Cross-Functional Integration: Build and lead multi-skilled teams with clinical, regulatory, data science, and project management partners to craft integrated development plans and compelling narratives. • Global Technical Stewardship: Provide expert consultation to internal stake-holders worldwide and ensure consistent adoption of statistical standards, methods, and tools across regions. • Regulatory Engagement: Lead or guide statistical content for regulatory interactions, including briefing books, responses, and advisory meetings, aligning evidence packages with international expectations. • Innovation and Methods Development: Investigate, develop, and apply modern statistical and quantitative approaches, including adaptive designs, advanced modeling, and real-world data integration, to improve insight, speed, and robustness. • Quality and Compliance: Ensure all statistical work meets AstraZeneca standards and external regulations, maintaining the integrity of analyses, interpretations, and reporting. • Information Governance: Drive effective planning, documentation, and communication of statistical strategies, results, and assumptions to enable transparent, auditable decisions. • Proposal and Vendor Oversight: Oversee statistical assessment of proposals and provide leadership to internal and external statisticians assigned to projects, ensuring proper overs