Manager of Bioinformatics (Oncology Product Development)

Natera is currently seeking a Bioinformatics Manager to join the Bioinformatics team focused on Oncology Product Development. In this role, the individual will manage a team of Bioinformaticians and Data Scientists and provide technical leadership in the design, development and validation of ctDNA-based diagnostic tests. This position requires extensive cross-functional collaboration with biostatistics, molecular biology, software engineering and commercial departments. The ideal candidate will have a strong background in bioinformatics and data science, optimally with experience in the LDT assay development space, and an established record of project and technical leadership. PRIMARY RESPONSIBILITIES: • Provide technical leadership for product development projects by representing the bioinformatics team in cross-functional interactions and moving products through the full development process through validation and commercial launch. • Lead the effort to optimize workflows, improve tools and pressure test analysis pipelines for diagnostic tests, including the detection of cancer-associated variants and the implementation of evidence-based quality control thresholds. • Supervise bioinformatics scientists and data scientists, managing their technical contributions, prioritizing resources, and taking responsibility for their technical and professional development. • Provide input on experiment design, analysis and interpretation based on expert understanding of Natera’s technology and relevant mathematical principles. • Work at a high level of independence and responsibilities in carrying out assignments. • Contribute to our intellectual property portfolio. • Set standards for rigorous data analysis and lead the production of high-quality documentation. QUALIFICATIONS: Requirements: • Master’s degree or Ph.D. in a quantitative discipline (bioinformatics, engineering, applied mathematics, statistics, or similar). • Minimum of 4-8 years of post-graduate experience in a data science and/or bioinformatics role and 1-3 years of experience as technical lead in diagnostics or a related field • Experience moving algorithm-based products through commercialization and launch in a medical or biological application such as diagnostic testing, medical imaging, or biotechnology • 1-2 years of management experience leading a technical team with demonstrable evidence of leadership and team management skills. Desirable, but not required: • Prior experience analyzing cancer-associated variant detection data KNOWLEDGE, SKILLS, AND ABILITIES: • Experience using Python or R for scientific data analysis and visualization. • Strong foundation in statistical modeling/machine learning, including probability theory and estimation/classification methods. • Experience with analysis of next-generation sequencing data, preferably including algorithm development or optimization. • Proven ability to apply mathematical principles to solve real estimation problems and implement practical solutions. • Excellent analytical, problem-solving and decision-making skills to independently make sound judgments and find creative solutions to moderately complex problems. • Experience leading technical projects, including defining and meeting project milestones, delegating tasks to more junior team members, and ensuring the quality of technical deliverables. • Excellent communication skills and the desire to work in a dynamic and collaborative environment. The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor consideration