Head of Medical & Scientific Affairs - Respiratory & Immunology

Head of Medical & Scientific Affairs - Respiratory & Immunology London Advert Closing Date: 18th November 2026 Introduction to role: Are you ready to lead medical strategy that transforms national standards of care for patients managing respiratory disease? We are seeking a highly experienced Medical Affairs leader with deep expertise in Respiratory & Immunology, spanning both inhaled therapies and biologics. This leader brings the strategic vision and leadership needed to develop and deliver world-class medical strategy. They will lead cross-functional teams, work closely with key NHS stakeholders, and support the successful launch of innovative therapies. You will provide strategic medical leadership to our Respiratory & Immunology Business Unit. You will craft business strategy and operational plans across functions using deep insight into healthcare professionals’, patients’, and payers’ needs. In this role, you will ensure an integrated medical strategy is in place across each R&I sub-therapy area. This will include optimising patient pathways and influencing organisational and healthcare policy. It involves leading external advocacy and delivering practice-changing initiatives. You will also advance real-world evidence generation and craft regulatory and market access strategy. This is alongside deploying AstraZeneca services and collaborative programmes. As an enterprise leader and scientific ambassador for AstraZeneca externally, you will use a broad clinical network spanning R&I therapy areas. You will lead the development of scientific launch strategies for pipeline products and ensure their successful execution in the field. You will provide inclusive leadership to the medical and scientific team, ensuring the medical strategy is carried out efficiently. Achieve agreed key targets and deliver clear reporting to the Medical Director and Senior Leadership Team. You will also play a key role in building organisational capability through coaching, targeted development and hiring, while representing the UK in regional and global Medical Affairs teams and helping maintain AstraZeneca UK as a leading launch market. Accountabilities: Scientific, Strategic and Launch Excellence: Define and implement comprehensive national and regional medical strategy for priority brands, aligned to and shaping global plans. Deliver "transforming care" initiatives that accelerate the speed and quality of care in asthma and COPD, develop world-class medical assets that demonstrate scientific leadership, and lead pre-launch market-shaping and launch readiness for pipeline assets, including through UK Pod planning from L-4 years. Build and offer expert medical input into regulatory and market access planning with partners in Regulatory Affairs and Market Access. This includes MHRA and NICE/SMC submissions, formulary, and protocol pathways to develop an environment for successful adoption of new medicines. Embed digital and data-driven approaches across the medical strategy, using analytics and insight to prioritise activity and direct effort and resource to the highest-value opportunities. Drive health system & clinical practice change Lead “Transforming Care” initiatives with the NHS and other partners across the patient pathway to drive population-level improvement in outcomes, support national policy reform and the pull-through of guidelines and quality standards, and accelerate access to optimal care. Field Medical Strategy and Execution: Provide leadership for MSL and Healthcare Delivery Partner teams. Define engagement strategies and critical metrics, deploy services strategically, build KEE networks, and create robust insight loops into medical, brand and account plans. Support P2/3 study set-up and recruitment and strengthen sci