Senior Manager, Business Assessment

Business Assessment (BA) is an exciting, highly collaborative, and dynamic team of professionals responsible for generating the investment cases for all pipeline and business development decisions. BA's assessments are independent by design: our credibility rests on applying the same rigor whether the analysis supports or challenges the case for investment. BA sits within Pfizer’s Global Commercial Analytics (GCA) organization under the Chief Marketing Office — a center of analytical excellence that unifies revenue forecasting across BD, in-line, and pipeline assets and elevates BA's strategic contribution across the full asset lifecycle.  Our BA team is valued for proactive thought leadership, epi-forecasting expertise, innovative analytical capabilities, and ability to communicate complex and dynamic information in clear, concise, and creative ways.    The BA Senior Manager owns discrete commercial assessments and forecasts end to end — building the model, framing the assumptions, and defending both — to inform investment decisions, partnering with colleagues across Research & Development, Global Commercial Strategy, the US and International commercial organizations, and Business Development (BD) to objectively evaluate internal pipeline and external opportunities against strategy and investment criteria.  The Senior Manager works with a high degree of independence and is expected to be hands-on in the underlying models rather than directing others' analysis, ensuring thorough and consistent information to inform critical internal investment decisions and structure appropriate external deal terms.     The Senior Manager will also provide strategic input into trade-off decisions that may be required between investment options, ensure consistency in assessment and forecasting approaches across external or internal investment options, and present analysis and recommendations directly to executive governance bodies.   The role is anchored in Inflammation & Immunology (I&I) and Specialty Care, covering a broad set of disease areas including respiratory, dermatology, gastroenterology, rheumatology, and rare cardiovascular. Beyond I&I and Specialty Care, the Senior Manager will also cover disease area opportunities across multiple therapeutic areas (oncology, internal medicine, vaccines), emerging technology platforms, and novel modalities — breadth of portfolio exposure that few commercial roles offer. ROLE RESPONSIBILITIES • Build and own assessments of pipeline and BD opportunities — including epidemiology-based patient flow, treatment exposure, uptake and diffusion curves, gross-to-net price build, and risk-adjusted NPV — collaborating closely with cross-functional partners to ensure the analysis is rigorous, transparent, and based on common and well-supported modeling techniques and assumptions • Take and defend an independent position — including recommending against an opportunity when the analysis does not support it, and doing so on incomplete information when the decision timeline requires it. This independence is the core of BA's value to Pfizer. • Gather input from key internal expert stakeholders on the potential clinical development plan or clinical profile and commercial evaluation (e.g., Global Commercial Strategy – both early and global commercial, Integrated Insights & Strategy, Medical Affairs, Global Access Strategy & Pricing, Global Marketing/Regional leaders in the US and International Commercial Organization, Research and Development, Finance) • Integrate in-line and BD/pipeline forecasts - connect BD/pipeline assessments to in-line assumptions, cannibalization logic, and Long-Range Forecast (LRF) revenue projections • AI-enabled assessment - use AI tooling as a standard part of the workflow: evidence and l