Jobs / United States / Astrazeneca Pharmaceuticals Lp
Scientist, High Throughput Antibody Production
Astrazeneca Pharmaceuticals Lp · 🇺🇸 US - Cambridge Kendall SQ - MA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Astrazeneca Pharmaceuticals Lp paid sponsored hires in similar roles3 certified filings for “Senior Scientist, High-Throughput Experimentation (HTE)” (Biochemists and Biophysicists) in MA: $139k–$142k, median $141k. Most were filed at wage level II (67%) — 2 lottery entries, ≈31% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Astrazeneca Pharmaceuticals Lp
The US Department of Labor certified 99 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 31 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Astrazeneca Pharmaceuticals Lp →
About the role
Biologics Engineering (BE) is a large, global organization with teams in Cambridge, UK; Gaithersburg, MD; and Cambridge, MA. We discover and optimize next-generation biologics for therapeutic areas including oncology, respiratory and immunology, and cardiovascular, renal and metabolic diseases. Our Cambridge, MA team is building an innovation center and lighthouse laboratory that combines scientific expertise, high-throughput automation, robotics, and digital orchestration to expand what is possible in biologics discovery. Through close collaboration across disciplines and geographies, we deliver high-quality therapeutic molecules that advance the R&D pipeline and address unmet patient needs. Role Summary: We are seeking a highly organized, detail-oriented Scientist to join our High-Throughput Production (HTP) team in Cambridge, MA. The successful candidate will use an advanced, integrated robotics laboratory to routinely produce, purify, and quality-control hundreds of antibodies and antibody-like therapeutic molecules each week in support of R&D pipeline programs. Working within validated, end-to-end automated workflows designed to enable near-lights-out production, this role is accountable for reliable execution, complete documentation, instrument and material readiness, and timely delivery of high-quality samples and data. Success requires hands-on high-throughput production experience, fundamental knowledge of protein expression and purification, disciplined adherence to detailed SOPs and instructions, exceptional attention to detail, and a collaborative team-first mindset. The primary focus is consistent operational delivery; the Scientist will also identify and communicate deviations, risks, and practical opportunities to improve workflow reliability. Main Duties & Responsibilities · Execute scheduled, high-throughput transient expression, purification, and sample-preparation campaigns for antibodies, multispecifics, and recombinant fragments, routinely supporting delivery of hundreds of molecules per week across R&D pipeline programs. · Operate liquid handlers and integrated robotics platforms, including Hamilton and Lynx systems and Cellario orchestration software, using approved methods; complete deck setup, barcode and consumable checks, run monitoring, recovery steps, and basic troubleshooting in accordance with SOPs. · Prepare media, reagents, plates, and consumables; culture CHO and HEK293 cells; perform aseptic transient transfections; harvest via filtration or centrifugation in accordance with SOPs. · Perform routine production and QC testing according to established methods, including concentration, purity, identity, and other fit-for-purpose biochemical, biophysical, or functional measurements; assess results against acceptance criteria and compile complete, traceable data packages for project teams. · Track samples, inventory, and metadata in laboratory logistics/LIMS software to maintain chain-of-custody and ensure timely delivery and data completeness. · Maintain automation and analytical instrumentation readiness through preventive maintenance, calibrations, and upkeep of equipment logs; coordinate vendor service when required. · Coordinate daily work with HTP colleagues and cross-functional partners to meet weekly throughput, quality, and turnaround targets; communicate status, dependencies, deviations, and delivery risks clearly and promptly. · Follow detailed SOPs, work instructions, and production schedules precisely; recognize and escalate departures from expected performance, and contribute practical observations that strengthen process robustness and operational consistency. · Engage with AI/ML and automation tools as they are introduced into workflows, and actively contribute ideas for improving d