Jobs / United States / Generate Biomedicines INC
Senior Director, Scientific Project Lead (Oncology)
Generate Biomedicines INC · 🇺🇸 Somerville, MA
Sponsorship verdict
Sponsorship possible
One solid signal, not two — worth applying, and worth asking about sponsorship early.
- Employer is on a government sponsor recordThe US Department of Labor certified 14 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 2 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
- The posting doesn’t mention sponsorshipSilence isn’t a refusal — ask the recruiter before investing much time.
- No salary bar for this routeH-1B has no fixed salary bar: the employer must pay at least the prevailing wage for the role and area. Cap-subject employers enter a lottery weighted by wage level. Source: https://www.federalregister.gov/documents/2025/12/29/2025-23853/weighted-selection-process-for-registrants-and-petitioners-seeking-to-file-cap-subject-h-1b, rules effective 2026-02-27.
- What Generate Biomedicines INC paid sponsored hires in similar roles1 certified filing for “Associate Director, Statistical Programming” (Data Scientists) in CA: $195k–$195k, median $195k. Most were filed at wage level IV (100%) — 4 lottery entries, ≈61% projected selection odds for cap-subject employers. Source: US Department of Labor LCA disclosure data (Oct 2025 – Jun 2026).
- Confirmed live todayWhen a source last listed this job as open.
US H-1B: cap-subject employers enter a lottery weighted by wage level — Level I gets 1 entry, Level IV gets 4 (DHS projected selection odds ≈15% at Level I to ≈61% at Level IV). Universities and non-profit research employers are cap-exempt. The $100,000 fee for new petitions from abroad is currently blocked by a court order (appeal pending).
A verdict summarises public evidence; it is not legal advice and never a guarantee — the employer and the immigration authority decide. Sign in to factor in where you can already work.
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Sponsor Radar — Generate Biomedicines INC
The US Department of Labor certified 14 H-1B/E-3 labor condition applications for this employer between Oct 2025 and Jun 2026 (latest Jun 2026) — the step every H-1B hire needs first. USCIS also records 2 H-1B approvals in FY2023. Source: LCA disclosure data (US Department of Labor (OFLC)).
Past sponsorship or register membership never guarantees sponsorship for this vacancy or for you. Full Sponsor Radar for Generate Biomedicines INC →
About the role
The Role: Generate is seeking a Senior Director, Scientific Project Lead, Oncology to lead complex, cross-functional scientific programs from concept and early discovery through preclinical development, contribute to translational and early development strategy, and manage and develop scientific talent. This role combines formal people management with broad cross-functional leadership across research, platform, translational, preclinical, development, and portfolio functions. Working closely with functional , business and technical leaders, project managers , and senior and executive stakeholders, the Scientific Project Lead will bring deep scientific judgment in therapeutic discovery, strategic program leadership, and operational rigor to align multidisciplinary teams, guide key decisions, represent programs in governance forums, and contribute to portfolio prioritization. Here's how you will contribute: • Lead complex, cross-functional programs from concept and early discovery through preclinical development, with accountability for scientific strategy, execution quality, team effectiveness, risk management, and stage-gate readiness. • Develop and maintain integrated program strategies and plans that align scientific objectives , timelines, dependencies, critical path activities, and resourcing. • Set scientific program direction and identify and advance therapeutic opportunities and target proposals by integrating disease biology, Generate’s differentiated platform capabilities, internal and external evidence, translational and clinical rationale, and competitive intelligence. • Facilitate cross-functional discussions, resolve divergent perspectives, make clear recommendations, own key scientific decisions within the project team structure, and drive timely go/no-go recommendations. • Drive execution across wet lab, computational, platform, translational, and preclinical workstreams, ensuring scientific rigor, reproducibility, strong documentation, and high-quality data packages. • Develop resource plans and budget assumptions, anticipate strategic inflection points, and proactively resolve risks, gaps, and cross-functional dependencies. • Build effective operating mechanisms for program planning, governance preparation, risk tracking, decision-making, and cross-functional accountability. • Manage, coach, and develop direct reports through clear objectives , regular feedback, performance management, compensation recommendations, and career development; mentor cross-functional team members in partnership with their functional managers. • Set clear expectations and foster a high-performing team culture grounded in scientific rigor, accountability, transparency, urgency, collaboration, and constructive challenge. The Ideal Candidate will have: • PhD, MD, or MD/PhD in cancer biology, immun o -oncology , or another discipline relevant to therapeutic discovery and development. • 12+ years of r elevant experience in biotech, pharma, academia, or a related scientific environment. • Experience identifying , evaluating, or advancing therapeutic targets and preclinical programs in oncology. • Experience designing or interpreting preclinical oncology studies, including in vitro functional assays, in vivo efficacy models, and pharmacodynamic or mechanistic studies that connect mechanism to clinically meaningful hypotheses. • Experience managing and developing scientists or other technical professionals, combined with a strong record of leading multidisciplinary teams through influence. • Experience shaping program strategy, influencing senior stakeholders, and synthesizing complex scientific issues into sound decisions and clear governance recommendations, sometimes with incomplete information, while navigating scientific